Medical research

Enzyme necessary for development of healthy immune system

Mice without the deoxycytidine kinase (dCK) enzyme have defects in their adaptive immune system, producing very low levels of both T and B lymphocytes, the major players involved in immune response, according to a study by ...

Diseases, Conditions, Syndromes

H1N1 flu jab linked to small risk of nervous disorder

Vaccination in the United States against H1N1 "swine" flu, which swept the world in 2009-10, carried a small but tolerable risk of Guillain-Barre syndrome, a disorder that can cause muscle weakness or temporary paralysis, ...

Immunology

Modulating immune responses

The protein Roquin plays a key role in the regulation of immune reactions. LMU researchers have now uncovered details of the mechanism by which it controls the function of regulatory T cells in the adaptive arm of the immune ...

Immunology

Worms and germs lead to better immune function

A growing body of evidence in the medical community holds that greater diversity of bacteria and even worms in the digestive tract offers protection against a variety of allergic and autoimmune problems.

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Autoimmune diseases arise from an inappropriate immune response of the body against substances and tissues normally present in the body. In other words, the immune system mistakes some part of the body as a pathogen and attacks its own cells. This may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.

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