Oncology & Cancer

Too much of a good thing may lead to too much of a liver as well

All life is challenged by oxidants—reactive molecules or compounds that remove electrons from other molecules—often with adverse effect, commonly referred to as oxidative stress. Consequently, all organisms have evolved ...

Diabetes

A better diagnosis of rare diabetes to adapt treatment

Diabetes affects more than 400 million people worldwide and is a major public health problem. Although commonly referred to as a single disease, it actually constitutes a group of metabolic disorders with hyperglycaemia as ...

Diseases, Conditions, Syndromes

Lower income linked to certain kidney diseases

A new study found an inverse association between socioeconomic status and certain kidney diseases. The findings appear in an upcoming issue of CJASN.

Oncology & Cancer

Targeting turncoat immune cells to treat cancer

A Ludwig Cancer Research study has identified a mechanism by which regulatory T cells, which suppress immune responses, adapt their metabolism to thrive in the harsh microenvironment of the tumor. This mechanism, the study ...

Immunology

Research pinpoints rogue cells at root of autoimmune disease

There are more than 100 different autoimmune diseases. But what unites them all is that they arise from an individual's own cells—rare and mysterious immune cells that target not external viruses and bacteria but the body's ...

HIV & AIDS

Mathematicians develop a model of the movement of immune cells

Mathematicians from RUDN University have developed a computational model that allows predicting the mobility of T-lymphocytes, immune cells that recognize and destroy viruses. The model will help in the treatment of immune ...

Diseases, Conditions, Syndromes

New mouse model for celiac disease to speed research on treatments

Researchers at the University of Chicago have developed the first truly accurate mouse model of celiac disease. The animals have the same genetic and immune system characteristics as humans who develop celiac after eating ...

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Autoimmune diseases arise from an inappropriate immune response of the body against substances and tissues normally present in the body. In other words, the immune system mistakes some part of the body as a pathogen and attacks its own cells. This may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.

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