Immunology

Research team discovers body's own anti-inflammatory substance

A team of scientists led by Professor Karsten Hiller from the Braunschweig Center for Systems Biology BRICS has discovered an endogenous, anti-inflammatory substance: mesaconic acid. This molecule could be a drug candidate ...

Arthritis & Rheumatism

Most common allergies not linked to rheumatoid arthritis

Most common allergies are not associated with the risk for rheumatoid arthritis (RA), but some allergic conditions, including animal dander allergy and atopic dermatitis, are associated with increased RA risk, according to ...

Genetics

Researchers find that RNA exosome is key for B cell development

New research from UT Southwestern suggests that RNA exosomes—the cellular machines that degrade old molecules of RNA—play a key role in the development of B cells, which are critical to the immune system's ability to ...

Cardiology

New discoveries in lupus research

Two separate findings by a University of Houston nationally recognized expert in systemic lupus erythematosus (SLE or lupus), a chronic autoimmune disease that affects multiple organs including the kidneys, skin, joints and ...

Neuroscience

Nerve stimulation promotes resolution of inflammation

The nervous system is known to communicate with the immune system and regulate inflammation in the body. Researchers at Karolinska Institutet in Sweden now show how electrical activation of a specific nerve can promote healing ...

Diseases, Conditions, Syndromes

Kidney protein as potential target for treating autoimmune diseases

Approximately 23.5 million people in the U.S. have an autoimmune disease, and some studies suggest that number could be rising. New research using a mouse model for multiple sclerosis has uncovered a potential new area to ...

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Autoimmune diseases arise from an inappropriate immune response of the body against substances and tissues normally present in the body. In other words, the immune system mistakes some part of the body as a pathogen and attacks its own cells. This may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.

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