One of the main roles of the spleen is to help the body's immune system fight infections. The spleen does this through producing and regulating antibodies—antibody production is negatively affected in various conditions, ...
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LMU researchers have deciphered the complex interplay of various enzymes around the innate immune receptor toll-like receptor 7 (TLR7), which plays an important role in defending our bodies against viruses.
May 2, 2024
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The brain can direct the immune system to an unexpected degree, capable of detecting, ramping up and tamping down inflammation, shows a new study in mice from researchers at Columbia's Zuckerman Institute.
May 1, 2024
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Patients with rheumatoid arthritis (RA) all have a unique and diverse set of antibodies that are involved in the development of the disease. Researchers at Utrecht University unveiled the complexity of these antibodies using ...
May 1, 2024
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A team of researchers from Aarhus University has made a remarkable discovery that could improve cancer treatment and the treatment of a number of other illnesses. Their research is published in the journal Nature Communications.
Apr 30, 2024
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When pathogens invade the body, the immune system must react immediately to prevent or contain an infection. But how do our defense cells stay ready when no attacker is in sight?
Apr 24, 2024
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Autoimmune disease (AID) refers to the condition in which the immune system identifies the body's own cells and tissues as foreign, resulting in systemic inflammation. The immune system's self-attack via autoreactive B and ...
Apr 22, 2024
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White cells called regulatory B cells could be harnessed to fight cancers and to treat autoimmune diseases by either increasing or decreasing their function, as indicated by a new research.
Apr 17, 2024
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Four new studies led by Harvard Medical School researchers at Boston Children's Hospital reveal details about how B cells in the immune system churn out antibodies that become increasingly potent and specific after we're ...
Apr 12, 2024
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Genetic studies of diseases map segments of the genome driving disease. But to understand how those changes contribute to disease progression, it is important to understand how they may alter gene regulation of disease genes ...
Apr 9, 2024
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Autoimmune diseases arise from an inappropriate immune response of the body against substances and tissues normally present in the body. In other words, the immune system mistakes some part of the body as a pathogen and attacks its own cells. This may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.
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