Medical research

Study reveals new mode of triggering immune responses

Small proteins, called chemokines, that direct immune cells toward sites of infection can also form DNA-bound nanoparticles that can induce chronic, dysfunctional immune responses, according to a new study by researchers ...

Arthritis & Rheumatism

How mitochondrial damage ignites the 'auto-inflammatory fire'

Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and ...

Medications

New machine learning technique shows how drugs can be repurposed

A new machine learning method to model gene expression levels might improve the identification of genes that cause human diseases, according to a new study by Penn State College of Medicine researchers. Through information ...

Immunology

Research team discovers body's own anti-inflammatory substance

A team of scientists led by Professor Karsten Hiller from the Braunschweig Center for Systems Biology BRICS has discovered an endogenous, anti-inflammatory substance: mesaconic acid. This molecule could be a drug candidate ...

Arthritis & Rheumatism

Most common allergies not linked to rheumatoid arthritis

Most common allergies are not associated with the risk for rheumatoid arthritis (RA), but some allergic conditions, including animal dander allergy and atopic dermatitis, are associated with increased RA risk, according to ...

Genetics

Researchers find that RNA exosome is key for B cell development

New research from UT Southwestern suggests that RNA exosomes—the cellular machines that degrade old molecules of RNA—play a key role in the development of B cells, which are critical to the immune system's ability to ...

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