Autoimmune Diseases

Protein's role in lupus development

Northwestern Medicine scientists have demonstrated that the loss of a protein called Bim in macrophages—a type of immune cell—leads to the development of lupus-like disease in mice. The findings, published in the Journal ...

Dec 05, 2017
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7 skin care myths you thought were true

Itchy skin, bright rashes, dark blemishes, sun burns. Our skin changes all the time, but usually we don't give it much thought until we spot a pimple here or a bumpy rash there. But every day your skin has a long list of ...

Oct 31, 2017
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New approach for treatment of contact allergy

Researchers from the University of Bonn have isolated a molecule that is suitable for the control of contact allergies. The study illuminates a central immune mechanism, which may also play a role in other inflammatory diseases ...

Oct 30, 2017
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Modulating immune responses

The protein Roquin plays a key role in the regulation of immune reactions. LMU researchers have now uncovered details of the mechanism by which it controls the function of regulatory T cells in the adaptive arm of the immune ...

Dec 13, 2017
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Autoimmune diseases arise from an inappropriate immune response of the body against substances and tissues normally present in the body. In other words, the immune system mistakes some part of the body as a pathogen and attacks its own cells. This may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.

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