Two researchers from Huntsman Cancer Institute at the University of Utah (the U) have discovered a gene variant found in high-altitude Andean populations that they believe could be a new biomarker for predicting the severity ...
Dec 13, 2024
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Research led by Christian Medical College in Vellore, India, has demonstrated the successful use of lentiviral vectors to deliver gene therapy for patients with severe hemophilia A. The study presents a potential alternative ...
A new method can improve treatment for patients with chronic myeloid leukemia by predicting which medication will be most effective. The method also works for other forms of cancer where resistance may develop. A step is ...
Dec 4, 2024
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Women with a history of endometriosis and uterine fibroids might have an increased long term risk of premature death, finds a large study from the United States published by The BMJ .
Nov 21, 2024
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Like a fire alarm sending signals to evacuate a smoky building, the immune system has internal guards to help the body sense and respond to danger. However, for people with risks for heart disease, these warning signals can ...
Nov 13, 2024
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When people check in for their annual mammogram these days, some may face a surprising question: In addition to reviewing the mammogram for breast cancer, would the patient like the radiologist to examine the images for heart ...
Nov 2, 2024
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New research into the long-term dynamics of transplanted stem cells in a patient's body explains how age affects stem cell survival and immune diversity, offering insights that could make transplants safer and more successful.
Oct 30, 2024
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Our bodies divest themselves of 60 billion cells every day through a natural process of cell culling and turnover called apoptosis. These cells—mainly blood and gut cells—are all replaced with new ones, but the way our ...
Oct 23, 2024
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Metabolic disorders such as obesity, high blood pressure and non-alcoholic fatty liver diseases have been directly linked to an increased risk of developing bowel cancer, warn Flinders University researchers.
Oct 10, 2024
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Blood cancer patients of all races who receive cord blood transplants are now living longer.
Oct 1, 2024
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Hematological malignancies are the types of cancer that affect blood, bone marrow, and lymph nodes. As the three are intimately connected through the immune system, a disease affecting one of the three will often affect the others as well: although lymphoma is technically a disease of the lymph nodes, it often spreads to the bone marrow, affecting the blood and occasionally producing a paraprotein.
While uncommon in solid tumors, chromosomal translocations are a common cause of these diseases. This commonly leads to a different approach in diagnosis and treatment of hematological malignancies.
Hematological malignancies are malignant neoplasms ("cancer"), and they are generally treated by specialists in hematology and/or oncology. In some centers "Hematology/oncology" is a single subspecialty of internal medicine while in others they are considered separate divisions (there are also surgical and radiation oncologists). Not all hematological disorders are malignant ("cancerous"); these other blood conditions may also be managed by a hematologist.
Hematological malignancies may derive from either of the two major blood cell lineages: myeloid and lymphoid cell lines. The myeloid cell line normally produces granulocytes, erythrocytes, thrombocytes, macrophages and mast cells; the lymphoid cell line produces B, T, NK and plasma cells. Lymphomas, lymphocytic leukemias, and myeloma are from the lymphoid line, while acute and chronic myelogenous leukemia, myelodysplastic syndromes and myeloproliferative diseases are myeloid in origin.
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