Medical research
New research finds link between telomere length and lung disease
Brigham Young University biologist Jonathan Alder has a startling secret he doesn't freely share: he knows when most of us are going to die.
Feb 4, 2015
0
15
Bone Marrow Failure
Medical research
Stem cell transplant without radiation or chemotherapy pre-treatment shows promise
Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center report promising outcomes from a clinical trial with patients with a rare form of bone marrow failure who received a hematopoietic stem cell transplant ...
Dec 7, 2014
0
0
Medical research
Gene mutation discovered in blood disorder
An international team of scientists has identified a gene mutation that causes aplastic anemia, a serious blood disorder in which the bone marrow fails to produce normal amounts of blood cells. Studying a family in which ...
Sep 23, 2014
0
0
Medical research
Biochemical cascade causes bone marrow inflammation, leading to serious blood disorders
Like a line of falling dominos, a cascade of molecular events in the bone marrow produces high levels of inflammation that disrupt normal blood formation and lead to potentially deadly disorders including leukemia, an Indiana ...
Jul 3, 2014
0
0
Medical research
Possible explanation for human diseases caused by defective ribosomes
Ribosomes are essential for life, generating all of the proteins required for cells to grow. Mutations in some of the proteins that make ribosomes cause disorders characterized by bone marrow failure and anemia early in life, ...
Mar 31, 2014
0
0
Genetics
New disease gene discovery sheds light on cause of bone marrow failure
The study, published in The American Journal of Human Genetics, detected and identified a new disease gene (ERCC6L2). In its normal form, the gene plays a key role in protecting DNA from damaging agents, but when the gene ...
Feb 6, 2014
0
0
Oncology & Cancer
Genotyping of Aldehyde dehydrogenase2 (ALDH2) solves the mystery of Fanconi anemia
Kyoto University research group led by Prof. Minoru Takata has found the deleterious impact of the ALDH2 variant genotype in human Fanconi anemia (FA) patients. This finding strongly suggests the important role of endogenous ...
Jan 20, 2014
0
0
Oncology & Cancer
Age shouldn't limit access to transplants for MDS, study suggests
Patients with myelodysplastic syndromes (MDS) who were as old as 74 fared as well with stem cell transplantation as did patients in the 60-to-65 age range, according to a study from Dana-Farber Cancer Institute presented ...
Dec 7, 2013
0
0
Diseases, Conditions, Syndromes
Rare cause of anemia in newborns often overlooked, research suggests
Some babies diagnosed with and treated for a bone marrow failure disorder, called Diamond Blackfan Anemia, may actually be affected by a very rare anemia syndrome that has a different disease course and treatment, say scientists ...
Dec 7, 2013
0
0
Medical research
Modeling of congenital amegakaryocytic thrombocytopenia using iPS cell technology
A research group led by researcher Shinji Hirata and Professor Koji Eto at CiRA has conducted a study in which iPS cells generated from a patient with congenital amegakaryocytic thrombocytopenia (CAMT) were induced to differentiate ...
Aug 1, 2013
0
0
