An iron-binding drug that is already approved for treatment of other diseases could provide a novel way to attack ovarian tumors, according to a new study led by Weill Cornell Medicine researchers. The preclinical study, ...
Jul 29, 2024
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An analysis of pre-treatment tumor specimens from 105 patients with localized muscle-invasive bladder cancer found that the presence of a mutation in any one of three genes, all known to be involved in DNA damage repair, ...
Jul 29, 2024
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A combination of two drugs was capable of suppressing tumors in a non-conventional manner. Instead of inhibiting tumor cell division, as the most widely used medications do, the strategy consisted of hyperactivating oncogenic ...
Jul 26, 2024
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University of Toronto researchers have identified two genes that play a critical role in tumor growth in the pancreas—findings that have significant implications for understanding and treating pancreatic cancer.
Jul 25, 2024
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Receptor protein tyrosine phosphatases are cell membrane-localized proteins. They are regulators of cell-cell contacts and are also considered likely to be tumor suppressors, but the specifics of how they function are unknown. ...
Jul 24, 2024
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In cases where cancer is fatal, 9 out of 10 times the culprit is metastasis. This is when the primary tumor has sent out cells, like seeds, and invaded other organs of the body. While medicine has made great progress in treating ...
Jul 24, 2024
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As part of a breast cancer diagnosis, pathologists take cells from a biopsy and check them under a microscope. Most cancerous cells form roundish clumps, known as no special type, or invasive ductal carcinoma (IDC). In fewer ...
Jul 24, 2024
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A team of researchers at NYU Abu Dhabi, led by Professor Sehamuddin Galadari, has discovered that the tumor suppressor protein Prostate apoptosis response-4 (Par-4) can cause a unique type of cell death called ferroptosis ...
Jul 23, 2024
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Researchers in the lab of Jean Cook, Ph.D., chair and professor in the Department of Biochemistry and Biophysics, have identified the cellular processes that occur when you take a cancer drug meant to stop rapid cell growth ...
Jul 19, 2024
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Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children's Medical Center Research Institute ...
Jul 19, 2024
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