CAR T cell therapy, the breakthrough method of supercharging patients' T cells in the lab to attack cancer when re-infused, has worked more effectively against cancers of the blood than solid tumors.
Researchers have discovered that stomach cancers make electrical connections with nearby sensory nerves and use these malignant circuits to stimulate the cancer's growth and spread.
Feb 19, 2025
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Researchers at Dana-Farber Cancer Institute collaborated with multiple institutions to pinpoint rare germline structural variants as risk factors for non-blood-related cancers in children, including tumors in various organs. ...
A multi-institutional clinical trial led by the University of Navarra, Spain, found that blocking growth differentiation factor 15 (GDF-15) can counteract resistance to anti-PD-1 and anti-PD-L1 therapies in solid tumors.
Institute of Immunobiology-led research has made a significant breakthrough in understanding how the body combats lung cancer. Their study reveals that specific cells, known as fibroblastic reticular cells (FRCs), create ...
Triple negative breast cancer is the most aggressive subtype of the disease and is notorious for a poor prognosis, but scientists are working on a breakthrough method of converting these treatment-resistant tumors into a ...
Medical investigators are theorizing that a combination of two treatments that activate myeloid cells may effectively treat a recalcitrant form of pancreatic cancer that thwarts conventional immunotherapy.
The resistance to cancer treatment is often credited to the heterogenous cellular nature within a tumor. The tumor cell-cell interaction and cell-microenvironment have a key role in the invasion and progression of tumors ...
There's no question that tumor cells are notoriously skilled masters of immune disguise and, in many ways, real-life versions of what it's like hiding under the fictional invisibility cloak highlighted in the Harry Potter ...
A group of researchers led by the Dana-Farber Cancer Institute, Boston, has illustrated the mechanistic pathway for PTEN-deficient breast cancer and successfully tested a method of countering the downstream effects of immune ...
