Diseases, Conditions, Syndromes

Why severe fatty liver leads to liver damage

In hepatic steatosis, hepatocytes "die," resulting in liver damage. Severe steatosis increases hepatocellular deaths, thus aggravating liver damage. The mechanism is unclear. Using mice, we show that mild steatosis causes ...

Surgery

New scoring system to fix sex disparity in liver transplants

Every year, some 13,000 people are added to the liver transplant waiting list in the United States, but fewer than 9,000 receive a liver. Placement on the list largely depends on a number called the MELD (model for end-stage ...

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