Medications
FDA OKs first generic for Gleevec leukemia pill
U.S. regulators have approved the first generic version of one of the first very effective—and expensive—cancer drugs, Gleevec, which costs about $10,000 a month.
Dec 4, 2015
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Chronic Myeloid Leukemia
Oncology & Cancer
Could common diabetes drugs help fight leukemia?
Common diabetes drugs might help eradicate drug-resistant cancer cells in a certain form of leukemia when added to standard treatment, a small new study suggests.
Sep 2, 2015
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104
Diseases, Conditions, Syndromes
Tyrosine kinase inhibitors seem safe in CML with CKD
(HealthDay)—Tyrosine kinase inhibitors (TKIs) appear to be safe in patients with chronic-phase (CP) chronic myeloid leukemia (CML) and chronic kidney disease (CKD), according to a study published online July 28 in Cancer.
Aug 1, 2015
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Oncology & Cancer
Leukemia thwarted by cutting off link to environmental support
A new study by researchers at University of California, San Diego School of Medicine reveals a protein's critical - and previously unknown—role in the development and progression of acute myeloid leukemia (AML), a fast-growing ...
Jul 23, 2015
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21
Oncology & Cancer
Current blood cancer drug prices not justified, study finds
The costs associated with cancer drug prices have risen dramatically over the past 15 years, which is of concern to many top oncologists. In a new analysis, researchers at The University of Texas MD Anderson Cancer Center ...
Jun 23, 2015
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Medical research
Lean despite many calories
Metabolism experts are increasingly convinced that obesity and many of the pathogenic changes it entails, such as Metabolic Syndrome and type 2 diabetes, are a result of chronic inflammatory processes in fatty (adipose) tissue. ...
Jun 8, 2015
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Oncology & Cancer
Leukemia like Achilles, has its own weakness
Leukemia cells from chronic myeloid leukemia patients, especially those in the advanced stage, lack the BRCA1 protein. Importantly, the protein is not present even if the patient carries the proper, unmutated gene responsible ...
Mar 26, 2015
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Oncology & Cancer
Evolution may hold the key to more designer cancer drugs like Gleevec
This is the story of Abl and Src—two nearly identical protein kinases whose evolution may hold the key to unlocking new, highly specific cancer drugs.
Feb 19, 2015
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107
Oncology & Cancer
Could there be a gleevec for brain cancer?
The drug Gleevec (imatinib mesylate) is well known not only for its effectiveness against chronic myeloid leukemia (CML) and acute lymphoblastic leukemia, but also for the story behinds its development. The drug was specifically ...
Feb 9, 2015
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Oncology & Cancer
A new approach to fighting chronic myeloid leukemia
Chronic myeloid leukemia develops when a gene mutates and causes an enzyme to become hyperactive, causing blood-forming stem cells in the bone marrow to grow rapidly into abnormal cells. The enzyme, Abl-kinase, is a member ...
Nov 17, 2014
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