Diabetes
Could type 2 diabetes be managed with a simple outpatient procedure?
Gregory Ginsberg, a Penn Medicine doctor, is exploring a new frontier in the treatment of type 2 diabetes.
Jan 29, 2020
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Fatty Liver Disease
Medical research
New drug prevents liver damage, obesity and glucose intolerance in mice on high-fat diet
Mice given a new drug targeting a key gene involved in lipid and glucose metabolism could tolerate a high-fat diet regimen (composed of 60% fat from lard) without developing significant liver damage, becoming obese, or disrupting ...
Jan 21, 2020
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Diseases, Conditions, Syndromes
Obesity crisis blamed for a rise in fatty liver disease amongst young adults
One in five young people have fatty liver disease (steatosis), with one in 40 having already developed liver scarring (fibrosis), research published today [15 January] has found. The study, published in The Lancet Gastroenterology ...
Jan 16, 2020
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Diseases, Conditions, Syndromes
Nonalcoholic steatohepatitis will pose clinical, economic burden
Nonalcoholic steatohepatitis (NASH) is expected to pose a significant clinical and economic burden during the next 20 years for U.S. patients with type 2 diabetes mellitus (T2DM), according to a study published online Jan. ...
Jan 15, 2020
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Genetics
Form of severe malnutrition linked to DNA modification
A group led by researchers at Baylor College of Medicine has identified significant differences at the epigenetic level—the chemical tags in DNA that help regulate gene expression—between two clinically distinct forms ...
Dec 19, 2019
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Health
Perinatal exposure to flame retardant alters epigenome, predisposing metabolic disease
Studies have shown that perinatal exposure of rats and mice to common flame retardants found in household items permanently reprograms liver metabolism, often leading later in life to insulin resistance and non-alcoholic ...
Dec 13, 2019
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Health
Diet, not exercise, may be key to addressing our biggest cause of liver disease
Edith Cowan University researchers have found that a chronic disease affecting up to 80 per cent of overweight people may be causing an iron deficiency that simply leaves them too tired to get off the couch.
Dec 11, 2019
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Diseases, Conditions, Syndromes
Lactobacillus balances gut microbiome and improves chronic-alcohol-induced liver injury
Researchers demonstrated that Lactobacillus rhamnosus can dose-dependently reestablish a balanced intestinal microbiome and counter the liver-damaging effects of alcohol consumption in mice to reverse the results of chronic ...
Dec 10, 2019
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Medical research
3-D model of human liver for better diagnosis
Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and distinguishing different ...
Dec 3, 2019
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Diseases, Conditions, Syndromes
A novel, non-invasive MRI-based functional liver imaging score (FLIS) for investigating chronic liver disease
An interdisciplinary MedUni Vienna team has shown that important information about the stage and prognosis of chronic liver diseases can be gotten by functional magnetic resonance imaging (fMRI). Lying in a tube-like machine, ...
Nov 20, 2019
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