Medications
New treatment approved for rare form of hemophilia
(HealthDay)—Obizur (antihemophilic factor recombinant) has been approved to treat a rare, non-inherited form of hemophilia in adults.
Oct 24, 2014
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Hemophilia
Medications
Long-acting clotting agent approved for form of hemophilia
The drug Alprolix has been approved by the U.S. Food and Drug Administration as the first long-acting hemophilia B clotting agent, the FDA said in a news release.
Mar 31, 2014
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Medical research
New gene therapy targets hemophilia
Researchers at the UNC School of Medicine and the Medical College of Wisconsin found that a new kind of gene therapy led to a dramatic decline in bleeding events in dogs with naturally occurring hemophilia A, a serious and ...
Dec 11, 2013
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Medications
How to stop bleeding in the ER caused by warfarin
Prothrombin complex concentrates (PCCs) are faster and more effective than fresh frozen plasma at reversing hemorrhage caused by the anti-coagulant warfarin, despite plasma being the most commonly used therapy. A literature ...
Aug 2, 2013
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Genetics
Empty decoys divert antibodies from neutralizing gene therapy in cell, animal studies
Gene therapy researchers have produced a bioengineered decoy that fools the immune system and prevents it from mistakenly defeating the benefits delivered by a corrective gene. The decoy was effective in animal studies, and ...
Jul 17, 2013
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Medications
FDA approves rixubis for prophylactic tx in hemophilia B
(HealthDay)—Rixubis (coagulation factor IX recombinant) has been approved by the U.S. Food and Drug Administration to prevent routine bleeding episodes in people aged 16 and older with hemophilia B, the agency said in a ...
Jun 28, 2013
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Immunology
Scientists develop new technique to selectively dampen harmful immune responses
The human immune system is remarkably efficient, but sometimes its attack is misdirected, leading to allergies, autoimmune diseases and rejection of transplant organs and therapeutic drugs. Current immune suppressants have ...
Jun 3, 2013
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Genetics
Persistence pays off in solving hemophilia mystery, showing curiosity drives discovery
An Australian researcher has found the third and final missing piece in the genetic puzzle of an unusual form of hemophilia, more than 20 year after he discovered the first two pieces.
Mar 7, 2013
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Medical research
Sibling study discovers genetic region linked to control of key blood-clotting protein
In 2006, the lab of Dr. David Ginsburg at the Life Sciences Institute put a call out for siblings attending the University of Michigan to donate blood for a study of blood-clotting disorders.
Jan 8, 2013
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Diseases, Conditions, Syndromes
Into adulthood, sickle cell patients rely on ER
Patients with sickle cell disease rely more on the emergency room as they move from pediatric to adult health care, according to researchers at Washington University School of Medicine in St. Louis.
Dec 10, 2012
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