People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time. The cause is related to expansion of repeating DNA units, in which specific strings of genetic ...
Jan 9, 2025
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University of Bergen researcher Markus Miettinen is among the first scientists to provide a detailed description of protein clumps associated with Huntington's disease. The findings, which could pave the way for new diagnostic ...
Jan 7, 2025
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The genetic mutation that causes Huntington's disease (HD)—a devastating brain disease that disrupts mobility and diminishes cognitive ability—may also enhance early brain development and play a role in promoting human ...
Nov 13, 2024
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Scientists at Northwestern and Case Western Reserve universities have developed the first polymer-based therapeutic for Huntington's disease, an incurable, debilitating illness that causes nerve cells to break down in the ...
Nov 1, 2024
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Researchers with McMaster University have discovered that the protein mutated in patients with Huntington disease doesn't repair DNA as intended, impacting the ability of brain cells to heal themselves.
Sep 27, 2024
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For the first time, researchers have implicated the gene CHCHD2 in Huntington's disease (HD)—an incurable genetic neurodegenerative disorder—and identified the gene as a potentially new therapeutic target. In a brain ...
Aug 22, 2024
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In Huntington's disease, the mutant huntingtin gene (HTT) mRNA is retained in the nucleus and forms insoluble clusters. A new study shows that short interfering RNA (siRNA), an oligonucleotide therapeutic strategy that reduces ...
Jul 22, 2024
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Research led by UCLA Health reveals that Black patients with Huntington's disease in the U.S. and Canada received their diagnoses, on average, one year later compared to white patients after symptoms first appear.
Jul 10, 2024
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The genetic disease Huntington's not only affects nerve cells in the brain but also has widespread effects on microscopic blood vessels according to research.
Jun 9, 2024
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Weizmann Institute scientists have discovered two small molecules that can cross the blood-brain barrier in mice, slowing and even reversing the effects of Huntington's, which is incurable.
Feb 26, 2024
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