During the 1990s, medicinal chemist Anders Hallberg was working in his lab at the Department of Medicinal Chemistry. He was exploring a hormonal system in the body that regulates blood pressure, among other things, by designing ...
Nov 18, 2024
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Medical science has long been on the hunt for a deeper understanding of the devastating scarring of the body's organs known as fibrosis, which leads to irrevocable loss of function.
A woman's ovaries are like a factory where eggs grow and produce hormones that regulate everything from menstruation and pregnancy to bone density and mood. As she and her factory age, production dwindles, and by the time ...
Sep 16, 2024
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Fibrotic hypersensitivity pneumonitis is a chronic and progressive interstitial lung disease, caused by an immune response to inhaled foreign antigens or allergens. Researchers from Yale's Section of Pulmonary, Critical Care ...
Aug 27, 2024
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A study from China has reported that Cordyceps sinensis (CS), a traditional Chinese medicinal fungus, can ameliorate idiopathic pulmonary fibrosis (IPF) in mice by inhibiting mitochondrion-mediated oxidative stress.
Jul 26, 2024
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A new research paper titled "Modulating in vitro lung fibroblast activation via senolysis of senescent human alveolar epithelial cells" has been published in Aging.
Jul 17, 2024
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Drugs that selectively kill senescent cells may benefit otherwise healthy older women but are not a "one-size-fits-all" remedy, Mayo Clinic researchers have found. Specifically, these drugs may only benefit people with a ...
Jul 2, 2024
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Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease marked by the thickening and scarring of lung tissue with unclear etiology. Affecting around five million people worldwide, IPF causes severe respiratory ...
Jun 12, 2024
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Patients with pulmonary fibrosis from the poorest areas had more severe symptoms by the time they saw a hospital doctor and had a poorer survival rate than those living in wealthier areas, according to the new research.
May 9, 2024
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Pulmonary diseases are a leading cause of morbidity and mortality worldwide. For many progressive lung diseases like idiopathic pulmonary fibrosis (IPF), a key issue is a low supply of new stem cells to repair and reverse ...
Apr 10, 2024
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Idiopathic pulmonary fibrosis (IPF) (or cryptogenic fibrosing alveolitis (CFA) / or Idiopathic Fibrosing Interstitial Pneumonia) is a chronic, progressive form of lung disease characterized by fibrosis of the supporting framework (interstitium) of the lungs. By definition, the term is used only when the cause of the pulmonary fibrosis is unknown ("idiopathic").
Microscopically, lung tissue from patients shows a characteristic set of histologic/pathologic features known as usual interstitial pneumonia (UIP). UIP is therefore the pathologic counterpart of IPF.
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