A study led by biomedical scientists at the University of California, Riverside School of Medicine shows how a genetic mutation associated with Crohn's disease can worsen iron deficiency and anemia—one of the most common ...
Jun 8, 2025
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A research team led by the Borzage Laboratory at Children's Hospital Los Angeles tested a new functional magnetic resonance imaging (fMRI) analysis method to measure cerebrovascular health in aging adults. What they found ...
May 27, 2025
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Findings from a recent study suggest iron deficiency anemia (IDA) independently and significantly increases the odds of ischemic stroke in young adults. The research is published in the journal eJHaem.
May 16, 2025
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Iron deficiency—when there's too little iron in the blood—may affect a quarter of the world's population, and in particular, women of reproductive age. Symptoms can include fatigue and shortness of breath, and without ...
May 8, 2025
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Women with polycystic ovary syndrome (PCOS) tend to have higher average ferritin levels compared to control subjects, but this does not seem to have a significant impact on their fertility or metabolic health. Iron deficiency ...
Apr 28, 2025
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New research from the University of Oklahoma sheds light on an understudied area of science: iron levels in the blood and their relationship to cognitive performance in women transitioning into menopause. The findings are ...
Apr 28, 2025
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New research published in BJOG: An International Journal of Obstetrics & Gynaecology has found that mothers who are anemic in early pregnancy face a higher likelihood of giving birth to a child with a heart defect.
Apr 23, 2025
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Teenage girls who avoid meat in favor of a plant-based diet are at higher risk of developing an iron deficiency, according to our latest research.
Apr 16, 2025
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Among iron-deficient patients with heart failure with reduced ejection fraction (HFrEF), receiving intravenous iron supplementation was found to be safe but resulted in mixed findings, according to a study presented at the ...
Mar 31, 2025
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Multiple menopause symptoms can make women feel fatigued. Hot flashes, sleep problems, pain, and depression are just a few. A new study suggests that heavy or prolonged menstrual bleeding may increase fatigue, which helps ...
Mar 12, 2025
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Iron deficiency (sideropenia or hypoferremia) is one of the most common of the nutritional deficiencies. Iron is present in all cells in the human body, and has several vital functions. Examples include as a carrier of oxygen to the tissues from the lungs in the form of hemoglobin, as a transport medium for electrons within the cells in the form of cytochromes, and as an integral part of enzyme reactions in various tissues. Too little iron can interfere with these vital functions and lead to morbidity and death.
The direct consequence of iron deficiency is iron deficiency anemia. Children and pre-menopausal women are the groups most prone to the disease.
Total body iron averages approximately 3.8 g in men and 2.3 g in women. In blood plasma, iron is carried tightly bound to the protein transferrin. There are several mechanisms that control human iron metabolism and safeguard against iron deficiency. The main regulatory mechanism is situated in the gastrointestinal tract. When loss of iron is not sufficiently compensated by adequate intake of iron from the diet, a state of iron deficiency develops over time. When this state is uncorrected, it leads to iron deficiency anemia.
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