Diseases, Conditions, Syndromes

More than half of Amazonian armadillos carry leprosy

The bacteria that causes leprosy, a chronic disease that can lead to disfigurement and nerve damage, is known to be transmitted to humans from nine-banded armadillos. A new study in PLOS Neglected Tropical Diseases reports ...

Diseases, Conditions, Syndromes

Publication details IDRI's promising leprosy vaccine candidate

A publication in Nature Partner Journals (npj) Vaccines indicates that post-exposure prophylaxis with LepVax, IDRI's leprosy vaccine candidate, not only appears safe but, unlike BCG (a tuberculosis vaccine that provides some ...

Diseases, Conditions, Syndromes

Researchers characterize unusual blood clots in leprosy patients

For years, doctors have observed that some patients with leprosy develop unusual blood clots which can lead to stroke or heart attack. Now, researchers reporting in PLOS Neglected Tropical Diseases have for the first time ...

Diseases, Conditions, Syndromes

Leprosy's drug resistance and origin revealed by genome analysis

Leprosy is an infectious disease with gruesome symptoms. It damages the skin, peripheral nerves, the upper respiratory tract, and the eyes. Despite being curable with multidrug therapy, leprosy still persists in many developing ...

Diseases, Conditions, Syndromes

Promising new leprosy vaccine moves into human trials

Today marks a significant step forward in the prevention and treatment of leprosy as the Infectious Disease Research Institute (IDRI) and American Leprosy Missions announce the start of a Phase 1 clinical trial in humans ...

Immunology

Leprosy turns the immune system against itself, study finds

Leprosy hijacks our immune system, turning an important repair mechanism into one that causes potentially irreparable damage to our nerve cells, according to new research that uses zebrafish to study the disease. As such, ...

Diseases, Conditions, Syndromes

Immune suppressant ineffective in treating leprosy inflammation

Throughout the course of a leprosy infection, patients often have episodes of painful inflammation affecting their skin and nerves. Researchers have continuously struggled with finding effective drugs to treat these so-called ...

Diseases, Conditions, Syndromes

Leprosy strain genotyped from medieval pilgrim at UK burial site

Leprosy is a bacterial infection caused by Mycobacterium leprae or Mycobacterium lepromatosis. It has afflicted humans for thousands of years, reaching epidemic levels during the Middle Ages, and people continue to be affected ...

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