Liver cirrhosis is significantly more common in low-income households than in high-income households, according to a national study which, according to the researchers, calls for more preventive action in the most vulnerable ...
Oct 28, 2025
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Imagine a condition affecting nearly one-third of the global population, often silently progressing, and deeply intertwined with prevalent health issues like obesity and type 2 diabetes. This is metabolic dysfunction-associated ...
A team of Mount Sinai surgeons has performed the first heart-liver-kidney triple organ transplants in New York. They successfully completed two of these complex surgeries on patients from Westchester County, who have since ...
May 20, 2025
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A pioneering research study published today in Cell Metabolism details how the hormone FGF21 (fibroblast growth factor 21) can reverse the effects of fatty liver disease in mice. The hormone works primarily by signaling the ...
May 13, 2025
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A Chinese woman is the third person in the world living with a gene-edited pig kidney, and nearly three weeks after surgery, doctors say she's doing well.
Mar 30, 2025
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Researchers from Columbia University and the German Cancer Center have found that stellate cells—star-shaped liver cells long known as the main perpetrators of liver fibrosis—have a commanding role in protecting and sustaining ...
Mar 12, 2025
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UCLA Health researchers have discovered significant changes in liver function following exposure to diesel exhaust (DE) in a controlled study involving mice. The study identified disrupted activity in 658 genes and 118 metabolites. ...
Mar 4, 2025
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New research from the University of Pittsburgh School of Pharmacy sheds light on the processes that lead to liver fibrosis and suggests a novel treatment approach for this common and serious condition.
Sep 25, 2024
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Formerly known as nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory disease characterized by liver scarring or fibrosis that progressively impairs liver function.
Aug 22, 2024
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Liver cells have a vital metabolic inflexibility during regeneration to starve dysfunctional cells and keep damage from spreading, according to new research from Children's Medical Center Research Institute at UT Southwestern ...
Jul 26, 2024
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Liver function tests (LFTs or LFs), are groups of clinical biochemistry laboratory blood assays designed to give information about the state of a patient's liver. The parameters measured include PT/INR, aPTT, albumin, billirubin (direct and indirect) and others. According to some, liver transaminases (AST/ALT (SGOT/SGPT) are not liver function tests, but are biomarkers of liver injury in a patient with some degree of intact liver function.[citation needed] Other sources include transaminases. Most liver diseases cause only mild symptoms initially, but it is vital that these diseases be detected early. Hepatic (liver) involvement in some diseases can be of crucial importance. This testing is performed by a medical technologist on a patient's serum or plasma sample obtained by phlebotomy. Some tests are associated with functionality (e.g., albumin); some with cellular integrity (e.g., transaminase) and some with conditions linked to the biliary tract (gamma-glutamyl transferase and alkaline phosphatase). Several biochemical tests are useful in the evaluation and management of patients with hepatic dysfunction. These tests can be used to (1) detect the presence of liver disease, (2) distinguish among different types of liver disorders, (3) gauge the extent of known liver damage, and (4) follow the response to treatment. Some or all of these measurements are also carried out (usually about twice a year for routine cases) on those individuals taking certain medications- anticonvulsants are a notable example- in order to ensure that the medications are not damaging the person's liver.
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