A Cleveland Clinic-led clinical trial of tolebrutinib, an investigational oral Bruton's tyrosine kinase inhibitor, a group of drugs originally developed to treat lymphomas and related blood disorders, demonstrated a 31% delay ...
Apr 8, 2025
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Researchers from Critical Path Institute's (C-Path) Predictive Safety Testing Consortium have proposed glutamate dehydrogenase (GLDH) as a more liver-specific biomarker for detecting liver injury, supporting clearer decision-making. ...
Mar 28, 2025
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Sarepta Therapeutics said Tuesday that a patient died while taking its closely watched gene therapy for muscular dystrophy, sending company shares plummeting more than 25%.
Mar 18, 2025
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Over the last 20 years, vast advancements in the field of biotechnology have led to the development of a research approach called multi-omics, which looks at multiple layers of biological informationālike gene expression, ...
Nov 12, 2024
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Botanicals like turmeric, green tea and black cohosh may seem benign, but their overuse is being increasingly linked to liver injury.
Aug 5, 2024
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Excessive alcohol intake is strongly associated with alcohol-associated liver disease (ALD) which accounts for 25% and 30% of deaths from cirrhosis and hepatocellular carcinoma. Impairment of Ca2+ influx and Ca2+-mediated ...
Jan 17, 2024
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Currently, the United States lacks FDA-approved treatments for liver fibrosis, highlighting the critical need to understand the cellular biology and pathways associated with this condition.
Nov 1, 2023
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In a study published in the journal of Genes & Diseases, a team of researchers from Chonnam National University and the Korea Research Institute of Bioscience and Biotechnology unveiled important insights into liver injury ...
Sep 14, 2023
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In two separate studies, researchers at EPFL have carried out extensive tests to develop the best mouse models for studying kidney and liver diseases. The findings provide crucial insights into both conditions, and are expected ...
Feb 21, 2023
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COVID-19 infection is associated with increased liver stiffness, a sign of possible long-term liver injury, according to the results of a new study being presented today at the annual meeting of the Radiological Society of ...
Dec 1, 2022
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