Medications

FDA: Samsca may cause irreversible liver damage

(HealthDay)—Patients who take Samsca (tolvaptan) may be at elevated risk for significant liver injury, according to a Jan. 25 safety alert issued by the U.S. Food and Drug Administration.

Addiction

Binge drinking can dramatically amplify damage to the liver

Alcoholic liver disease (ALD) is characterized by a fatty liver, hepatitis, fibrosis, and cirrhosis. Binge drinking is on the rise worldwide, and is particularly common in the U.S. A review of studies addressing the effects ...

Medications

Signifor approved for Cushing's disease

(HealthDay)—Signifor (pasireotide diaspartate) has been approved by the U.S. Food and Drug Administration to treat Cushing's disease in cases that cannot be treated by surgery.

Diseases, Conditions, Syndromes

Dietary supplements can cause liver injury, warns expert

Dose-dependent (acetaminophen) and idiosyncratic drug-induced liver injuries (DILI) are the leading cause of acute liver failure in the United States and are responsible for approximately 50 percent of all reported cases.

Diseases, Conditions, Syndromes

NIH launches free database of drugs associated with liver injury

A free source of evidence-based information for health care professionals and for researchers studying liver injury associated with prescription and over-the-counter drugs, herbals, and dietary supplements is now available ...

Medical research

Solving the puzzle of drug-induced liver injury

Antibiotics are the first line of defense against many infections. But for some individuals, treatment with certain antibiotics can bring on a new set of health problems, including serious liver damage.

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