Currently, the United States lacks FDA-approved treatments for liver fibrosis, highlighting the critical need to understand the cellular biology and pathways associated with this condition.
Nov 1, 2023
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Liver injury is a rare side effect of nonsteroidal anti-inflammatory drugs (NSAIDs), which are frequently used for daily pain control. This toxicity has been regarded as a 'black box' and is mainly managed by an empirical ...
Jan 22, 2021
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Red yeast rice (RYR) is contained in dietary supplements that are often used by patients with high cholesterol, and it is often proposed as an alternative therapy in those who experience side effects from statins. A new study ...
Jan 17, 2017
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In an updated clinical guideline issued by the American College of Gastroenterology and published in the May issue of The American Journal of Gastroenterology, recommendations are presented for the diagnosis and management ...
Jun 7, 2021
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Antibiotics are the first line of defense against many infections. But for some individuals, treatment with certain antibiotics can bring on a new set of health problems, including serious liver damage.
Sep 13, 2012
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(HealthDay)—A first case of paintball-related blunt liver injury has been described in an article published online April 27 in BMJ Case Reports.
May 9, 2016
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Investigators at the Medical University of South Carolina (MUSC) have identified a critical regulatory mechanism for the production of nitric oxide (NO). Endothelial nitric oxide synthase (eNOS) is the enzyme responsible ...
May 2, 2017
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(HealthDay)—Idiosyncratic drug-induced liver injury (DILI) is mainly caused by antimicrobials and herbal and dietary supplements (HDS), according to research presented at the annual meeting of the American College of Gastroenterology, ...
Oct 20, 2014
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Scientists have discovered an uncommon genetic variation that may identify patients with a higher risk of liver damage associated with a range of commonly-prescribed medications.
Feb 22, 2017
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The farnesoid-X receptor (FXR), also known as the chief regulator of bile acid metabolism, is thought to play a role in some hepatobiliary and gastrointestinal disorders. In a study published in the American Journal of Pathology, ...
Jan 29, 2015
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