Arsenic is a natural element in the environment, sometimes found in air, soil and water. Arsenic contaminated water is a global threat, currently affecting more than 100 million people. Both genetic and epigenetic changes ...
Jul 25, 2012
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Inhibitors of indoleamine 2,3-dioxygenase (IDO) are being assessed in clinical trials as a potential treatment for recurrent or refractory solid tumors. Clear genetic rationale for these trials, together with evidence that ...
Jul 19, 2012
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One way to tackle a tumor is to take aim at the metabolic reactions that fuel their growth. But a report in the February Cell Metabolism shows that one metabolism-targeted cancer therapy will not fit all. That means that ...
Feb 7, 2012
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The investigational drug ganetespib, a synthetic second-generation Hsp90 inhibitor, slowed the growth of cancer cells taken from non-small cell lung cancer tumors with a mutation in the KRAS gene. The drug was even more active ...
Jan 11, 2012
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Multicentric carcinogenesis with the same genetic mutation appears to occur in lung adenocarcinoma, according to data presented at the AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Biology, Therapy and ...
Jan 9, 2012
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A combination of drugs that target estrogen production significantly reduced the number of tobacco carcinogen-induced lung tumors in mice, according to results from a preclinical study.
Jan 9, 2012
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A Wayne State University researcher has shown that compounds found in soybeans can make radiation treatment of lung cancer tumors more effective while helping to preserve normal tissue.
Dec 19, 2011
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Compared with other cities, Detroit has one of the highest mortality rates in the United States for non-small cell lung cancer (NSCLC). Based on data from the National Cancer Institute Surveillance, Epidemiology, and End ...
Oct 24, 2011
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Researchers at Brigham and Women's Hospital (BWH) have identified a new combination of targeted therapies that, together, may treat two aggressive tumor types that until now have not had effective treatments. These findings ...
Sep 12, 2011
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The journal Radiology will publish in its September issue an article written by Damian E. Dupuy, M.D., director of tumor ablation at Rhode Island Hospital, supporting the use of ablation procedures for the treatment of lung ...
Aug 31, 2011
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