Diseases, Conditions, Syndromes

New discovery paves way for next generation malaria vaccine

In an unprecedented first, scientists at Seattle Children's Research Institute have developed a genetically attenuated parasite (GAP) that arrests late in the liver stage of human malaria. Their findings published in JCI ...

Medications

FDA approves IV artesunate for severe malaria

Intravenous (IV) artesunate received approval from the U.S. Food and Drug Administration to treat adults and children with severe malaria, the agency announced Tuesday.

Diseases, Conditions, Syndromes

Malaria parasite ticks to its own internal clock

When a person gets malaria, a rhythmic dance takes place inside their body. The disease's telltale signs—cyclical fevers and chills—are caused by successive broods of parasites multiplying in sync inside red blood cells, ...

Medical research

Molecular signatures can predict the efficacy of malaria vaccines

Molecular signatures before and after immunization can predict vaccine-induced protection, according to a study by ISGlobal. The study analysed the gene expression in peripheral blood cells from individuals immunized with ...

Diseases, Conditions, Syndromes

Malaria vaccine: Could this 'ingredient' be the secret to success?

This ingredient is an essential component of the malaria parasite, a protein known as RPL6, which makes the parasite "visible" to a type of immune cells, the T cells, in the liver. The researchers added the protein to their ...

Diseases, Conditions, Syndromes

New evidence for optimizing malaria treatment in pregnant women

The research, published today in The Lancet Infectious Diseases is the fruit of joint project between investigators from around the world to conduct the largest individual patient data meta-analysis to date under the WWARN ...

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