Oncology & Cancer
New pediatric cancer marker: Hope for a treatment target
Researchers have newly identified a universal, essential biomarker for the childhood cancer neuroblastoma—and a potential new target for treatment.
Feb 28, 2024
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Neuroblastoma
Oncology & Cancer
Combining anti-tumor drugs with chemo may improve rare children's cancer outcomes
Children who develop neuroblastomas, a rare form of cancer which develops in nerve cells, may benefit from receiving certain anti-tumor drugs as well as chemotherapy, a new trial has found.
Jan 9, 2024
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Medical research
Researchers find Zika virus is effective when used to treat a type of childhood cancer in mice
Injecting neuroblastoma tumors with Zika virus shrank or eliminated those tumors in studies with mice, suggesting that the virus could someday serve as an effective cancer therapy, according to a study led by Nemours Children's ...
Jan 9, 2024
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Oncology & Cancer
Immune atlas at cell level points to new combination treatment for incurable childhood cancer
A detailed 'atlas' of neuroblastoma tumors points to a new target for immunotherapy. Scientists from the Princess Máxima Center for pediatric oncology in the Netherlands mapped this childhood tumor at the level of individual ...
Jan 4, 2024
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Oncology & Cancer
How research helped lead to FDA approval of a pediatric neuroblastoma drug
In 2003, the first year of her fellowship in pediatric oncology, two of Giselle Saulnier Sholler's first three patients had died from neuroblastoma, closely matching the 30% survival rate expected at the time for high-risk ...
Dec 15, 2023
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Oncology & Cancer
Discovery could lead to 'kinder' treatment for childhood neuroblastoma
Children with neuroblastoma—responsible for 15% of cancer deaths in this age group—could in future be given treatments with fewer side-effects than those associated with the current chemotherapy, thanks to a discovery ...
Sep 20, 2023
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Oncology & Cancer
New therapeutic approach for the treatment of neuroblastoma in young children
Neuroblastomas are tumors of the nervous system. They can form in many places in the body and are the most common cause of cancer-related deaths in young children. A team of researchers at University Medicine Halle has discovered ...
Aug 25, 2023
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Oncology & Cancer
Q&A: Cancer of the nerve cells
My 4-year-old niece recently was diagnosed with neuroblastoma after not feeling well for a few weeks. Her parents noticed her belly was swollen, so they took her to the doctor after it didn't resolve on its own. I'd never ...
Aug 1, 2023
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Oncology & Cancer
Childhood cancer: Vulnerability in the immune response against metastases discovered
Scientists led by Sabine Taschner-Mandl, Ph.D., St. Anna Children's Cancer Research Institute, and Nikolaus Fortelny, Ph.D., Paris Lodron University of Salzburg, are the first to analyze bone marrow metastases from childhood ...
Jun 26, 2023
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Oncology & Cancer
Lorlatinib found to be safe and effective for patients with ALK-driven relapsed/refractory high-risk neuroblastoma
In a significant step for the treatment of neuroblastoma, an international group of researchers led by Children's Hospital of Philadelphia (CHOP), Winship Cancer Institute of Emory University and the New Approaches to Neuroblastoma ...
Apr 3, 2023
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