Physician-scientists in the Cancer Center at Children's Hospital of Philadelphia (CHOP) have developed a preclinical, potent therapy attached to an antibody that targets a surface protein expressed in most childhood neuroblastomas, ...
Mar 13, 2019
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Dr. Kenneth Alexander was driving home one day last year when he thought of the idea: What if the Zika virus could be used to kill a childhood cancer called neuroblastoma?
Jul 25, 2018
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Proton therapy, using high-energy subatomic particles, may offer a precise, organ-sparing treatment option for children with high-risk forms of neuroblastoma. For patients in a new study of advanced radiation treatment, proton ...
Aug 13, 2013
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Neuroblastoma, a rare childhood cancer of the sympathetic nervous system, is particularly deadly because it is difficult to detect and thus generally advanced before treatment begins. Scientists know that neuroblastoma develops ...
Jul 6, 2018
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Preclinical research from VCU Massey Cancer Center published recently in the Proceedings of the National Academy of Sciences shows that the combination of two existing drugs can exploit the metabolic 'hunger' of a particularly ...
Mar 30, 2021
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Neuroblastoma is one of the most common and lethal types of childhood cancers. In a paper published online today in OncoTarget, a researcher at the University of Texas Health Science Center at San Antonio unveils the important ...
Mar 1, 2014
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Like a Russian bot corrupting U.S. elections, or a new prime minister wreaking havoc in the U.K., a protein named BORIS is showing itself to be a malevolent player in some childhood cancers. New research fingers BORIS as ...
Sep 25, 2019
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Neuroblastoma is a type of childhood cancer that develops in infants and young children. Whilst it is a relatively rare form of cancer, it is still responsible for approximately 15 percent of all cancer deaths in children. ...
Sep 7, 2021
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Anyone who has ever studied the molecular basis of breast cancer will probably have heard of BRCA1, a protein that protects the cells of breast tissue against cancer. Surprisingly, this protein can also have the opposite ...
Mar 20, 2019
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A type of drug known as a PARP inhibitor, already used to treat breast and ovarian cancer, may be useful in treating children with high-risk neuroblastoma—a common childhood tumor with a low survival rate.
Jun 25, 2020
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