Neuroscience

Diabetic foot pain: Expert tips on how to cope

An estimated 1 in 10 people worldwide have diabetes. Africa is the region with the fastest growth and it's estimated that the number of people on the continent with diabetes will more than double in the next 20 years, increasing ...

Diseases, Conditions, Syndromes

Why pain medication may not be as effective for women as it is for men

A new study led by University of Calgary professor Dr. Tuan Trang, Ph.D., may help to explain why there are more women experiencing chronic pain than men. In 2019, the Canadian Pain Task Force report found that chronic pain ...

Medical research

Cannabinoids offer new hope for safe and effective pain relief

Chronic pain is a global health challenge, with current treatment options often limited by side effects, addiction risk, and diminished effectiveness over time. In a new study, Yale researchers identify alternative compounds ...

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Neuropathic pain results from lesions or diseases affecting the somatosensory system. It may be associated with abnormal sensations called dysesthesia, which occur spontaneously and allodynia that occurs in response to external stimuli. Neuropathic pain may have continuous and/or episodic (paroxysmal) components. The latter are likened to an electric shock. Common qualities include burning or coldness, "pins and needles" sensations, numbness and itching. Nociceptive pain, by contrast, is more commonly described as aching.

Up to 7% to 8% of the European population is affected and in 5% of persons it may be severe. Neuropathic pain may result from disorders of the peripheral nervous system or the central nervous system (brain and spinal cord). Thus, neuropathic pain may be divided into peripheral neuropathic pain, central neuropathic pain, or mixed (peripheral and central) neuropathic pain.

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