Bone pain. Joint pain. Bone swelling. These are symptoms that about 1,000 people in the United States begin to feel each year shortly before being diagnosed with osteosarcoma, a type of cancer that starts in the bones. Although ...
Jan 17, 2025
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Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 and 20, during times of rapid bone growth. Although rare, it has a significant impact on young people ...
Jan 14, 2025
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Researchers have been able to identify at least three distinct subtypes of a rare type of bone cancer for the first time, which could transform clinical trials and patient care.
Dec 20, 2024
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A new review was published in Oncotarget on August 2, 2024, entitled, "Targeting WNT5B and WNT10B in osteosarcoma."
Sep 4, 2024
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Despite decades of advancement in treatment, cancer spreading to multiple parts of the body remains one of the biggest challenges facing patients and their health-care teams.
Sep 4, 2024
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Chimeric antigen receptor (CAR) T–cell immunotherapy re-engineers a patient's immune cells to target cancer cells. While successful in some types of leukemia, the approach has yet to realize its potential against pediatric ...
Aug 5, 2024
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In a study published in the journal Genes & Diseases, scientists from Union Hospital, Tongji Medical College, and Huazhong University of Science and Technology delve into the molecular intricacies of osteosarcoma in the elderly. ...
Dec 4, 2023
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The strangely named hedgehog pathway that's crucial to bone growth has emerged as a key in the fight to treat the bone cancer osteosarcoma.
Nov 28, 2023
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In a cancer that has not seen new targeted therapies for over 20 years, MUSC Hollings Cancer Center researcher and oncologist Nancy Klauber-DeMore, M.D., is pioneering new discoveries.
Jun 23, 2021
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A preclinical study led by researchers at The University of Texas MD Anderson Cancer Center shows an antibody-drug conjugate (ADC) targeting surface protein MT1-MMP can act as a guided missile in eradicating osteosarcoma ...
Apr 12, 2021
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Osteosarcoma is an aggressive malignant neoplasm arising from primitive transformed cells of mesenchymal origin (and thus a sarcoma) that exhibit osteoblastic differentiation and produce malignant osteoid. It is the most common histological form of primary bone cancer.
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