In a recent study, precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS mutations had higher-than-normal expression of the FGFR2 protein, and FGFR2 inactivation delayed KRAS-mutated ...
Apr 2, 2025
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As more people receive genetic testing after a cancer diagnosis, newer variants have been identified that increase the risk of developing cancer. A recent study led by the University of Michigan Rogel Cancer Center finds ...
Mar 27, 2025
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A new study by Mayo Clinic Comprehensive Cancer Center researchers found that the presence of a specific genetic mutation—KRAS circulating tumor DNA (ctDNA)—strongly indicates a higher risk of cancer spread and worse ...
Mar 19, 2025
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Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic cancer at bay in preclinical models for significantly longer than the same targeted therapy ...
Mar 14, 2025
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Researchers at the Garvan Institute of Medical Research have uncovered how pancreatic cancer hijacks a crucial metabolic "switch" to help it spread, revealing a potential new treatment strategy for this highly aggressive ...
Mar 14, 2025
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For cancers of organs like the liver, the long-term impact of our diet has been well studied—so much so that we have guidance about red meat, wine and other delicacies.
Mar 13, 2025
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Researchers have discovered race-associated molecular differences in tumors that may impact the way patients with pancreatic cancer respond to immunotherapies. The findings, which were recently published in the journal Cancer ...
Mar 12, 2025
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Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%. This poor prognosis stems from both late detection and the cancer's notorious capacity to adapt and resist therapy.
Mar 12, 2025
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Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and their collaborators demonstrated ...
Mar 10, 2025
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The KRAS G12C mutation is found in approximately 3% of all colorectal cancer cases and 1% to 2% of pancreatic adenocarcinoma cases, according to Hao Xie, MD, PhD, a medical oncologist at Mayo Clinic Comprehensive Cancer Center.
Mar 3, 2025
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