Some viral diseases could possibly contribute to neurodegeneration. DZNE researchers report this in the journal Nature Communications. Their assessment is based on laboratory experiments in which they were able to show that ...
Oct 19, 2021
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Case Western Reserve University researchers studying prions—misfolded proteins that cause lethal incurable diseases—have identified for the first time surface features of human prions responsible for their replication ...
Jun 17, 2021
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The earliest eye damage from prion disease takes place in the cone photoreceptor cells, specifically in the cilia and the ribbon synapses, according to a new study of prion protein accumulation in the eye by National Institutes ...
Jan 29, 2021
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One of the hallmarks of Alzheimer's disease is the formation of amyloid plaques—sticky clumps of a protein called amyloid beta—that collect between neurons in the brain. Increasingly, however, attention has turned from ...
Nov 2, 2020
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Antibodies targeting the normal PrP version of the prion protein have been found in humans selected at random with no history of any associated transmissible spongiform encephalopathies. The significance is that prion proteins ...
Aug 17, 2020
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A new study in Nucleic Acids Research, published by Oxford University Press, suggests a possible effective treatment strategy for patients suffering from prion disease.
Aug 10, 2020
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Human prion diseases include Creutzfeldt-Jakob disease (CJD) and Gerstmann-Sträussler-Scheinker disease (GSS). A new study in the open-access journal PLOS Biology reports a significant advance in the development of mouse ...
Jun 9, 2020
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In the fight against neurodegenerative diseases such as frontotemporal dementia, Alzheimer's and Chronic Traumatic Encephalopathy, the tau protein is a major culprit. Found abundantly in our brain cells, tau is normally a ...
Apr 2, 2020
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A new University of Toronto study sheds light on how protein strains vary in the brains of those affected by progressive neurodegenerative diseases like Parkinson's, suggesting the need for patient-specific medicines.
Dec 4, 2019
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There are currently no effective treatments for prion diseases, a family of fatal neurodegenerative conditions caused by accumulations of misfolded copies of a naturally occurring protein. But now, there is finally an effective ...
Nov 6, 2019
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