Patients with BRCA1/2 mutations are at higher risk for breast, ovarian and prostate cancers that can be aggressive when they develop—and, in many cases, resistant to lifesaving drugs. Now scientists at The University of ...
Sep 22, 2020
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30
With advances in genome sequencing, cancer treatments have increasingly sought to leverage the idea of "synthetic lethality," exploiting cancer-specific genetic defects to identify targets that are uniquely essential to the ...
Jul 27, 2020
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186
A team of researchers from Google Health, working with others from institutions across the U.S. and Canada has found that a Google AI system was able to outperform general pathologists when validating Gleason grading of prostate ...
When prostate cancer progresses to a more-dangerous metastatic state, it does so by resurrecting dormant molecular mechanisms that had guided the fetal development of the prostate gland but had been subsequently switched ...
Jul 20, 2020
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99
Cancer biologists at the Mays Cancer Center, home to UT Health San Antonio MD Anderson, have identified important drivers that enable tumors to change their behavior and evade anticancer therapies.
May 18, 2020
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Over the last decade, enzalutamide and similar drugs have led to significant tumor control and increased survival time for men who have metastatic prostate cancer that continues to grow despite treatments to reduce male hormone ...
Apr 27, 2020
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According to Statistics Austria about 5,600 men are diagnosed with prostate cancer in Austria every year, meaning it accounts for roughly a quarter of all cancers in men. For some the cancer develops slowly and requires minimal ...
Apr 23, 2020
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Prostate cancer is the most common malignancy among men in the United States. It is also the second most common cause of cancer-related deaths. Despite improved treatments for prostate cancer, many patients with advanced ...
Apr 9, 2020
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163
Although metastatic castration-resistant prostate cancer (mCRPC) typically has limited response to immunotherapy, a subset of patients with pretreatment evidence of active T-cell responses in their tumors experienced prolonged ...
Apr 1, 2020
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144
A very large team of researchers affiliated with institutions across China (and several from Washington University School of Medicine in the U.S.) has found recurrent alterations in prostate cancer in Chinese patients that ...
