A new article published in the Cell Reports describes how a new drug is able to reduce the symptoms and activate the dormant neurons characteristic of Rett syndrome in preclinical models. The study was led by Dr. Manel Esteller, ...
May 15, 2018
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Vanderbilt University researchers have relieved symptoms of Rett syndrome in a mouse model with a small molecule that works like the dimmer switch in an electrical circuit.
Aug 23, 2017
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New research into Rett syndrome therapeutics suggests that a small molecule already reported to improve respiratory problems associated with the disease may also improve spatial memory and motor skill defects.
Jul 5, 2017
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A translational, multicenter study has unveiled the potential of D-serine—a dietary supplement—to improve the neuronal function of a patient with a mutation of the glutamate receptors associated to atypical Rett syndrome ...
Jul 4, 2017
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Researchers at the University of Alabama at Birmingham are part of the international STARS study to see if a drug originally developed for Parkinson's disease might help reduce breathing issues common in patients with Rett ...
Dec 19, 2016
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A study led by the University of Utah School of Medicine provides new insights into how the subtle changes within cells, caused by disruptions in a gene called Kirrel3, could underlie some types of intellectual disability ...
Nov 17, 2015
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Using "mini-brains" built with induced pluripotent stem cells derived from patients with a rare, but devastating, neurological disorder, researchers at University of California, San Diego School of Medicine say they have ...
Sep 8, 2015
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The term intellectual disability covers a large number of clinical entities, some with known cause and others of uncertain origin. For example Down syndrome is due to an extra copy of chromosome 21 and Rett syndrome is in ...
Jul 20, 2015
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Independent reproduction of other scientists' results is a cornerstone of solid research, but scientists are rarely recognized for successfully reproducing published findings, much less for demonstrating that scientific findings ...
May 20, 2015
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New research by investigators at the University of Massachusetts Medical School suggests the immune system plays an unsuspected and surprising role in the progression of Rett syndrome, a severe neurological disorder affecting ...
May 11, 2015
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