A virus linked to cancer can hijack the host's cellular mail and could help drive changes in the environment around tumors, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center found.
Feb 22, 2019
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In patients with soft tissue sarcoma, the concomitant use of gastric acid suppressant (GAS) therapy and the anticancer therapeutic pazopanib (Votrient) was associated with significantly reduced progression-free survival and ...
Feb 14, 2019
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The RIG-I like receptors (RLRs) are intracellular enzyme sentries that detect viral infection and initiate a first line of antiviral defense. The cellular molecules that activate RLRs in vivo are not clear.
Dec 14, 2018
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AIDS patients suffer higher rates of cancer because they have fewer T-cells in their bodies to fight disease. But new research examines why HIV-infected patients have higher rates of cancer—among the leading causes of death ...
Dec 5, 2018
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Scientists have developed a potential new therapeutic approach for synovial sarcoma, one of the most common soft-tissue cancers in teenagers and young adults. At present the long-term survival rates for synovial sarcoma patients ...
Nov 20, 2018
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Among a small cohort of patients with HIV-associated Kaposi's sarcoma treated with immune checkpoint inhibitors, more than 65 percent had partial or complete remission.
Sep 7, 2018
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Scientists have discovered that some childhood bone cancers start growing years before they are currently diagnosed. Researchers at the Wellcome Sanger Institute and Hospital for Sick Children (SickKids), Canada discovered ...
Aug 30, 2018
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Sarcomas are rare tumors that are often misdiagnosed. Specific recurrent chromosomal rearrangements, known as translocations, can serve as essential diagnostic markers and are found in about 20 percent of sarcomas. Identification ...
Aug 20, 2018
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A Massachusetts General Hospital (MGH) research team has used epigenome editing tools to investigate how the genetic abnormality that drives Ewing sarcoma—the second most common bone cancer in children and young adults—unleashes ...
Aug 2, 2018
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Scientists at the University of Sheffield have discovered what keeps the perfect balance of breaks and repairs in our DNA—something which could help improve the success of chemotherapy and combat neurodegeneration associated ...
Jun 12, 2018
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