Sarcoma

How genetic mutations promote Ewing's sarcoma

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have elucidated at the molecular level how an otherwise innocuous inherited mutation that is quite common in European populations interacts with a spontaneous ...

Jul 28, 2015
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Non-HIV-related kaposi sarcoma in BRAFi-treated patient

(HealthDay)—In a case report published online Feb. 28 in the Journal of Clinical Pharmacy and Therapeutics, researchers document non-HIV-associated Kaposi sarcoma in a male patient with myasthenia gravis and metastatic ...

Mar 17, 2016
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Figitumumab has anti-tumor activity in Ewing's sarcoma

A preliminary study of the anticancer drug figitumumab has found that it has antitumour activity in Ewing's sarcoma—a cancer which affects mainly teenage boys. The results have led to the drug's progression to a Phase 2 ...

Dec 23, 2009
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Immunotherapy effective against some types of sarcoma

An existing cancer immunotherapy drug reduces tumor size in some types of rare connective tissue cancers, called sarcomas, report researchers at the University of Pittsburgh Cancer Institute (UPCI). Additional analyses of ...

Jun 06, 2016
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Possible new treatment for Ewing sarcoma

Discovery of a new drug with high potential to treat Ewing sarcoma, an often deadly cancer of children and young adults, and the previously unknown mechanism behind it, come hand-in-hand in a new study by researchers from ...

Nov 26, 2012
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New marker, new target in Ewing's sarcoma

Ewing's sarcoma is a bone cancer commonly diagnosed in about 250 U.S. teenagers per year. If early chemotherapy is effective, improvement can be durable. But for children and teens who respond poorly to a first attempt at ...

Jun 30, 2012
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A sarcoma (from the Greek sarx (σάρκα) meaning "flesh") is a cancer that arises from transformed cells of mesenchymal origin. Thus, malignant tumors made of cancerous bone, cartilage, fat, muscle, vascular, or hematopoietic tissues are, by definition, considered sarcomas. This is in contrast to a malignant tumor originating from epithelial cells, which are termed carcinoma. Sarcomas are quite rare - common malignancies, such as breast, colon, and lung cancer, are almost always carcinoma.

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