Diseases, Conditions, Syndromes

Hydroxyurea underused in youth with sickle cell

Few youths with sickle cell anemia (SCA) receive hydroxyurea despite national guidelines recommending its use, according to a study published online March 24 in JAMA Network Open.

Immunology

Study reframes understanding of graft-versus-host disease

New research challenges the prevailing hypothesis for how donor stem cell grafts cause graft-versus-host disease, or GVHD, and offers an alternative model that could guide development of novel therapies.

Diseases, Conditions, Syndromes

Hydroxyurea may reverse sickle cell-related heart abnormalities

Heart abnormalities are common complications of sickle cell anemia (SCA) that can contribute to severe disease symptoms and even death. A study published today in the journal Blood Advances is the first to find that hydroxyurea ...

Diseases, Conditions, Syndromes

Understanding sickle cell disease

Sickle cell disease, which is a group of inherited red blood cell disorders, affects approximately 100,000 people in the U.S., according to the Centers for Disease Control and Prevention.

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