Diseases, Conditions, Syndromes

COVID-19: Who's at higher risk of serious symptoms?

Over a year into the COVID-19 pandemic, it's important to remind people who is more at risk of serious coronavirus disease 2019 (COVID-19) symptoms, which can vary widely. Some people have no symptoms at all, while others ...

Diseases, Conditions, Syndromes

Toward a reliable oral treatment for sickle cell disease

For the millions of people worldwide who have sickle cell disease, there are only a few treatment options, which include risky bone marrow transplants, gene therapy or other treatments that address a subset of symptoms. Today, ...

Diseases, Conditions, Syndromes

A better treatment for sickle cell disease

Sickle cell disease is the most prevalent inherited blood disorder in the world, affecting 70,000 to 100,000 Americans. However, it is considered an orphan disease, meaning it impacts less than 200,000 people nationally, ...

Genetics

Addressing a complex world of pain in a single gene difference

A single letter difference in a single gene, inherited from both parents, spells a lifetime of anemia and pain for 20 million people, mostly of African ancestry, worldwide. Sickle cell disease (SCD) causes red blood cells ...

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