Bone marrow transplantation (BMT) can potentially cure sickle cell disease, an inherited and painful blood disorder, but because of its potential drawbacks and costs, patients and caregivers often face the difficult decision ...
Feb 27, 2025
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A bone marrow transplant process co-developed by investigators at the Johns Hopkins Kimmel Cancer Center is safe and curative for adults with sickle cell disease, according to results of a trial completed at Johns Hopkins ...
Feb 25, 2025
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Right now, approximately 20 billion red blood cells are busy traveling through your blood vessels. They are delivering oxygen to all the different tissues in your body and removing carbon dioxide to be breathed out of your ...
Feb 10, 2025
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A systematic literature review found no evidence to support that physical exertion without rhabdomyolysis (muscle breakdown) or heat injury can cause sudden death for individuals with sickle cell trait (SCT), nor is there ...
Jan 30, 2025
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Individuals with sickle cell disease—a chronic illness where misshapen, sticky blood cells clump together, reducing oxygen delivery to organs—are at a higher risk for stroke and resulting cognitive disability. But even ...
Jan 17, 2025
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The new gene therapies for sickle cell disease—including the gene-editing treatment Casgevy, based on research at Boston Children's Hospital—have been game-changing for the patients who have received them. But Stuart ...
Dec 18, 2024
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Though he doesn't remember it, Branden Baptiste had his first sickle cell crisis at age 2. Through elementary school, he was in and out of the hospital with pain episodes, not knowing why. As he got older, he learned he had ...
Dec 7, 2024
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Who doesn't love to cozy up with a hot water bottle during the colder months? Hot water bottles are a quick, easy and cost effective way of staying warm in winter—but they can also cause serious injury.
Dec 3, 2024
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Researchers described a promising new approach for using gene therapy to treat sickle cell disease in the journal Human Gene Therapy. To improve the efficacy of gene therapy when using anti-sickling beta globin gene transfer, ...
Nov 19, 2024
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Blood stem cells develop through different stages to become fully mature red blood cells. This fundamental biologic process is defined by a series of complex metabolic processes, which are often dysregulated in blood disorders ...
Nov 15, 2024
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