Genetics

Custom alterations: Mending genes for long-lasting effects

Gene-editing therapies—techniques that modify DNA to treat or prevent disease—have the potential to transform the field of drug development. By making precise edits to the genome, problematic genes could be modified or ...

Diseases, Conditions, Syndromes

Q&A: Shedding light on a neglected form of sickle cell disease

Sickle cell disease (SCD) is a group of painful and life-threatening genetic disorders that affect hemoglobin, the major protein that carries oxygen in red blood cells. It occurs in nearly 100,000 people in the United States ...

Medications

EU watchdog puts sickle cell disease drug on ice

The EU's drug watchdog Thursday called for the suspension of approval for Pfizer's medicine to treat sickle cell disease, saying doctors should stop using the drug.

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