Genetics
2019: the year gene therapy came of age
In the summer, a mother in Nashville with a seemingly incurable genetic disorder finally found an end to her suffering—by editing her genome.
Dec 5, 2019
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Sickle Cell Disease
Medical research
Newly approved sickle cell drug ushers in an era of therapeutic breakthroughs
Terri Booker's worst sickle cell crisis almost killed her.
Nov 27, 2019
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Cardiology
Youth with abnormal heart rhythms more likely to have ADHD, anxiety, depression
Children and teens with abnormal heart rhythms (cardiac arrhythmias) are more likely to have depression, anxiety and attention deficit hyperactivity disorder (ADHD) compared with those of similar ages without chronic medical ...
Nov 11, 2019
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Other
Survey suggests mentorship in medical school is vital to future of hematology
A survey of U.S. hematology-oncology fellows suggests medical school plays an important role in shaping their interest in pursuing careers in hematology, particularly when students are exposed to hematology and oncology as ...
Oct 31, 2019
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Other
US and Gates Foundation plan $200m for sickle cell, HIV cures
The US government and the Bill and Melinda Gates Foundation pledged Wednesday to jointly invest $200 million over the next four years to achieve affordable gene therapy-based cures for sickle cell disease (SCD) and HIV.
Oct 23, 2019
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Pediatrics
Social determinant screening useful for families with pediatric sickle cell disease
Individuals with sickle cell disease (SCD) face the burdens of chronic illness and often racial disparities, both of which may increase vulnerability to adverse social determinants of health (SDoH). For children with SCD, ...
Oct 10, 2019
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Health
Study shows reduced Illinois Medicaid spending in pediatric population, limited savings from care coordination
Researchers from the University of Illinois at Chicago are reporting in JAMA Network Open that Medicaid expenditures for children and young adults have decreased in Illinois. However, a care coordination demonstration project ...
Oct 4, 2019
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Medical research
Researchers create new viral vector for improved gene therapy in sickle cell disease
Researchers at the National Institutes of Health have developed a new and improved viral vector—a virus-based vehicle that delivers therapeutic genes—for use in gene therapy for sickle cell disease. In advanced lab tests ...
Oct 2, 2019
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Immunology
Uncovering new therapeutic targets for airway inflammation in sickle cell disease
A new study by De, Agrawal, Morrone et al, chal-lenges the common notion that airway inflammation in Sickle Cell Disease (SCD) is secondary to asthma, even though the two disorders often coexist. In a recent pilot, cross ...
Oct 1, 2019
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Medical research
For the first time, researcher observes crystallized iron product, hemozoin, made in mammals
Most people have some idea of how important iron is to their health, but Iqbal Hamza, professor in Animal and Avian Sciences, has made his seventeen-year career at the University of Maryland all about the study of iron and ...
Oct 1, 2019
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