Immunology

Impaired neutrophils in autoimmunity

Patients with autoimmune diseases such as systemic lupus erythematosus (SLE) have higher blood levels of the protein S100A9, but the source of this protein has not been identified.

Diseases, Conditions, Syndromes

Belimumab promising in combination therapy for refractory lupus

For patients with systemic lupus erythematosus (SLE) refractory to conventional treatment, belimumab after rituximab significantly reduces serum immunoglobulin (Ig)G anti-double stranded DNA (dsDNA) levels and the risk for ...

Diseases, Conditions, Syndromes

Managing inflammation through the endothelin system

Experts in the endothelin system are investigating how regulation of this system can serve to improve diseases of inflammation such as lupus. Endothelins are a class of peptides that play a role in regulating blood pressure. ...

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