Diseases, Conditions, Syndromes

UN agrees global plan to battle TB ahead of first-ever summit

UN member-states on Friday agreed on a global plan to step up the fight against tuberculosis, the world's number one killer among infectious diseases, settling a row with the United States over access to cheap drugs.

Diseases, Conditions, Syndromes

How damaging immune cells develop during tuberculosis

Insights into how harmful white blood cells form during tuberculosis infection point to novel targets for pharmacological interventions, according to a study published in the open-access journal PLOS Pathogens by Valentina ...

Diseases, Conditions, Syndromes

Scientists identify nearly 200 potential tuberculosis drug targets

Tuberculosis is one of the top 10 causes of death worldwide. Nearly 2 million people die every year from this infectious disease, and an estimated 2 billion people are chronically infected. The only vaccine, developed almost ...

Diseases, Conditions, Syndromes

Alcohol increases tuberculosis-related deaths in young mice

Alcohol increases the mortality of young but not old mice infected with the tuberculosis-causing bacterium Mycobacterium tuberculosis (Mtb), and this effect is mediated by the production of a protein called interferon-alpha ...

Diseases, Conditions, Syndromes

How Mycobacterium tuberculosis escapes death in macrophages

The bacteria that cause the devastating disease tuberculosis have the ability to escape destruction and grow after they are engulfed by lung macrophages, the immune cells that are supposed to destroy pathogens. Now researchers ...

Diseases, Conditions, Syndromes

Confronting TB resistance

Tuberculosis, caused by Mycobacterium tuberculosis, is a highly infectious lung disease in humans.Unfortunately, resistance to anti-tubercular medicines such as fourth-generation fluoroquinolones is on the rise. In most cases, ...

Diseases, Conditions, Syndromes

How attitudes to drug-resistant TB changed

The informal settlement of Khayelitsha in Cape Town is the latest site of a multi country trial that aims to transform the treatment for drug-resistant tuberculosis (DR-TB).

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