Pediatrics

New algorithms could improve pediatric tuberculosis diagnosis

Tuberculosis stands as one of the leading causes of death among young people across the world. Modeling studies suggest that in over 96% of the deadly cases involving children younger than 15 years old, the infected child ...

Medications

Oral deucravacitinib benefits patients with lupus

Tyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phase 2 clinical trial published in Arthritis & Rheumatology has ...

Diseases, Conditions, Syndromes

Oxygen responses of T cells alter protection against tuberculosis

In a new publication in Nature Communications, Martin Rottenberg and Ruining Liu, professor and Ph.D. student at the Department of Microbiology, Tumor and Cell Biology, explain how T cell protection against tuberculosis is ...

Genetics

New antibiotic resistance genes identified in tuberculosis

A massive analysis of more than 10,000 different Mycobacterium tuberculosis bacteria isolates from 23 countries has revealed new genes associated with resistance to 13 first- and second-line new and repurposed antibiotics. ...

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