Gastroenterology
Iron-mediated cell death linked to inflammatory bowel disease
New basic science insights into programmed cell death could offer relief for inflammatory bowel disease.
Jun 26, 2025
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15
Ulcerative Colitis
Inflammatory disorders
Unusual protein production in neutrophils may contribute to development of inflammatory bowel diseases
Scientists have discovered that certain immune cells—called neutrophils—can start making a protein called DUOX2 that they usually do not produce. This surprise activity may be fueling gut inflammation in conditions like ...
Jun 11, 2025
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21
Gastroenterology
Gut's energy crisis: How metabolism is severely disrupted in chronic inflammatory bowel diseases
Chronic inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, cause recurring diarrhea, fever, pain, and significant psychological distress. Despite major advances and modern medications, treatment ...
Jun 6, 2025
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61
Oncology & Cancer
Therapeutic target could prevent chronic gut inflammation from turning into cancer
Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic predisposition and certain factors ...
May 30, 2025
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15
Inflammatory disorders
New cause of chronic inflammation in ulcerative colitis discovered
It is estimated that more than 5 million people worldwide suffer from ulcerative colitis, a chronic inflammation of the colon that often progresses in stages whose causes have not yet been fully investigated. A new international ...
May 19, 2025
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32
Diseases, Conditions, Syndromes
Gut bacterium restores bile acid balance to heal intestinal injuries, offering potential ulcerative colitis treatments
The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health. When this microbial balance is disturbed, it can contribute to the development of chronic diseases like ulcerative ...
Mar 10, 2025
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248
Diseases, Conditions, Syndromes
Pair of studies identify promising new treatments for ulcerative colitis
According to the National Institutes of Health, between 600,000 and 900,000 Americans have ulcerative colitis, a chronic inflammatory disease of the large intestine.
Mar 5, 2025
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21
Oncology & Cancer
Scientists identify molecule that promotes gut regeneration and limits tumor growth
Researchers at Karolinska Institutet have found a molecule that can both help the intestines to heal after damage and suppress tumor growth in colorectal cancer. The discovery could lead to new treatments for inflammatory ...
Nov 20, 2024
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17
Diseases, Conditions, Syndromes
Combining 25 datasets, researchers map 1.6 million gut cells to find new ways treat disease
The most comprehensive cell map of the human gut to date has been created by combining spatial and single-cell data from 1.6 million cells.
Nov 20, 2024
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2
Diseases, Conditions, Syndromes
New study shows how salmonella tricks gut defenses to cause infection
A new UC Davis Health study has uncovered how Salmonella bacteria, a major cause of food poisoning, can invade the gut even when protective bacteria are present. The research, published in the Proceedings of the National ...
Nov 16, 2024
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