Zika virus and dengue virus are very close relatives. Both are mosquito-borne flaviviruses, and both specialize in infecting a host's dendritic cells.
Mar 25, 2025
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A team of Yale School of Medicine infectious diseases researchers recently conducted an in-depth review of the literature on how one genus of viruses, known as flaviviruses, manipulates mitochondria to evade immune responses. ...
Feb 26, 2025
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Record-breaking heat, extreme weather events, air pollution and the spread of infectious disease: climate change poses an already vast yet rising threat to the health of humans around the world, experts warn.
Nov 9, 2024
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Mosquito-borne illnesses are a growing concern in Northeastern states, with health officials monitoring cases and advising residents to avoid outdoor activities near standing water and other environments prone to mosquito ...
Oct 22, 2024
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The hospitalization last summer of Dr. Anthony Fauci, former head of the National Institute of Allergy and Infectious Diseases, with West Nile virus—and his account of it this week in the New York Times—have helped raise ...
Oct 8, 2024
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The U.S. is currently in the midst of yet another West Nile virus (WNV) outbreak, with the CDC documenting 880 cases across 46 states so far this year.
Oct 8, 2024
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Lyme disease is one of the most prevalent insect-borne diseases in the country, with far more cases each year than other diseases carried by mosquitoes, fleas and ticks, such as the West Nile virus.
Oct 3, 2024
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Climate change is exacerbating the risk of potentially dangerous mosquito-borne diseases in California—threatening to turn more of those annoying-but-harmless bites into severe illnesses, experts say.
Oct 1, 2024
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Eastern equine encephalitis (EEE) is a mosquito-borne disease that can induce severe fever, seizures, gastrointestinal issues and changes in behavior. About a third of EEE cases are lethal, and those who recover commonly ...
Sep 23, 2024
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Rhode Island's least favorite summer guests have arrived: mosquitos, especially those carrying eastern equine encephalitis (EEE) and West Nile Virus.
Sep 23, 2024
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West Nile virus (WNV) is a virus of the family Flaviviridae. Part of the Japanese encephalitis (JE) antigenic complex of viruses, it is found in both tropical and temperate regions. It mainly infects birds, but is known to infect humans, horses, dogs, cats, bats, chipmunks, skunks, squirrels, domestic rabbits, crows, robins, crocodiles and alligators. The main route of human infection is through the bite of an infected mosquito. Approximately 90% of West Nile Virus infections in humans are without any symptoms.
Image reconstructions and cryoelectron microscopy reveal a 45–50 nm virion covered with a relatively smooth protein surface. This structure is similar to the dengue fever virus; both belong to the genus Flavivirus within the family Flaviviridae. The genetic material of WNV is a positive-sense, single strand of RNA, which is between 11,000 and 12,000 nucleotides long; these genes encode seven non-structural proteins and three structural proteins. The RNA strand is held within a nucleocapsid formed from 12 kDa protein blocks; the capsid is contained within a host-derived membrane altered by two viral glycoproteins.
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