Uyen To, MD, assistant professor of medicine (digestive diseases) and transplant hepatologist, discusses how she first became interested in studying Wilson disease, the wide spectrum of symptoms caused by the rare condition, ...
May 11, 2023
0
2
Wilson's disease is a rare autosomal recessive disorder characterized by abnormal copper deposition in the liver, brain, cornea, and other tissues. It can lead to severe symptoms such as hepatitis, cirrhosis, and liver failure ...
May 9, 2023
0
22
A specific molecule excreted by methane-oxidizing bacteria could be most suitable for therapy against Wilson's disease (WD). This is what researchers led by Helmholtz Munich scientist Hans Zischka have found in a new study. ...
Mar 30, 2023
0
9
Your doctor may be the smartest, most compassionate, thoughtful person in the world—a leading specialist or someone you've trusted for years. But you shouldn't let that stop you from getting a second opinion.
Jan 23, 2020
0
1
Wilson disease (copper storage disease) is a rare genetic disorder in which one or more genetic mutations disrupt copper metabolism in the liver. At some point, the liver becomes incapable of eliminating copper with bile, ...
Feb 26, 2019
0
0
In the Journal of Clinical Investigation, scientists at the Helmholtz Zentrum München describe a small peptide that very efficiently binds excess copper from liver cells. This molecule comes from a bacterium's bag of tricks ...
Jun 21, 2016
0
3
Wilson disease is a genetic disorder in which copper accumulates to toxic levels in tissues, leading to neurological symptoms and liver disease. Diagnosis of the disease is challenging because symptoms can vary widely across ...
Jan 8, 2016
0
129
Geneva, Switzerland: The first European Clinical Practice Guidelines (CPGs) for the diagnosis and management of Wilson's disease are published today by the European Association for the Study of the Liver (EASL) on the EASL ...
Feb 7, 2012
0
0
Wilson's disease or hepatolenticular degeneration is an autosomal recessive genetic disorder in which copper accumulates in tissues; this manifests as neurological or psychiatric symptoms and liver disease. It is treated with medication that reduces copper absorption or removes the excess copper from the body, but occasionally a liver transplant is required.
The condition is due to mutations in the Wilson disease protein (ATP7B) gene. A single abnormal copy of the gene is present in 1 in 100 people, who do not develop any symptoms (they are carriers). If a child inherits the gene from both parents, the child may develop Wilson's disease. Symptoms usually appear between the ages of 6 and 20 years, but cases in much older people have been described. Wilson's disease occurs in 1 to 4 per 100,000 people. Wilson's disease is named after Samuel Alexander Kinnier Wilson (1878–1937), the British neurologist who first described the condition in 1912.
This text uses material from Wikipedia licensed under CC BY-SA
