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Endocrinology & Metabolism news
Oncology & Cancer
Research identifies key enzyme target to fight deadly brain cancers
Researchers have found that targeting an enzyme called PGM3 can help stop the growth of glioblastoma, the most dangerous type of brain tumor. Study findings are published online in the journal Science Advances.
Apr 18, 2025
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Gerontology & Geriatrics
Key enzyme in lipid metabolism linked to immune system aging
Our immune systems weaken as we get older, making fewer cells that fight infection and help us recover from illness and injury. Scientists aren't completely sure why. They may have a better idea now, however, thanks to a ...
Apr 18, 2025
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GLP-1 therapies show potential for treating rare genetic disorder Bardet-Biedl syndrome
A Monell Chemical Senses Center study published this week in the Journal of Clinical Investigation offers renewed hope for individuals living with Bardet-Biedl Syndrome (BBS), a rare genetic disorder characterized by early-onset ...
Apr 18, 2025
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Is intermittent fasting a helpful practice or health risk? A doctor explains
Although it may appear to be a new trend, intermittent fasting has been popular for over 1,500 years. While it is known that it works for some people to lose weight, the reality is that whether or not it helps organs such ...
Apr 18, 2025
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Study identifies link between body clock disruption and metabolic disease
Northwestern Medicine investigators have discovered how disruptions in the circadian rhythm in our muscles combined with poor diet can contribute to the development of diabetes, according to a recent study published in Proceedings ...
Apr 17, 2025
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Understanding why the kidneys are injured after cardiac surgery
Florey researchers, in collaboration with practicing clinicians who routinely care for heart surgery patients, have developed a world-first animal model to understand how cardiac surgery requiring the use of a heart-lung ...
Apr 17, 2025
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Cardiovascular disease: We know the impact of sex, but what role does gender play?
Cardiovascular disease (CVD) is the leading cause of death worldwide. According to the Global Burden of Disease study, which compiles and analyzes population health data from 204 countries, the number of CVD cases almost ...
Apr 17, 2025
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Oregon health officials investigate rare brain disease blamed for two deaths
Health officials in Hood River County, Oregon, are investigating three cases of a rare and fatal brain disease known as Creutzfeldt-Jakob disease.
Apr 17, 2025
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New research reveals socioeconomic influences on how the body regulates eating
Published in the journal Food Quality and Preference, new research highlights how physiological signals, particularly those transmitted via the vagus nerve, interact with socioeconomic factors to shape dietary behavior.
Apr 17, 2025
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Scientists achieve record-breaking growth in miniature, functional liver models
The liver is the body's control tower for metabolism, powering vital functions like converting nutrients to glucose, storing fat and breaking down toxins. Over a third of the world, however, is thought to be affected by conditions ...
Apr 16, 2025
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Emerging metabolic pathways in osteoarthritis: Insights from recent studies and therapeutic avenues
Osteoarthritis (OA) is one of the most prevalent conditions affecting tens of millions of U.S. adults, traditionally understood as a disease driven primarily by mechanical wear and tear. This perspective is being reshaped ...
Apr 16, 2025
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Unhealthy metabolic profile sharply increases risk of breast cancer return and subsequent death among survivors: Study
New research presented at the European Congress on Obesity (ECO 2025, Malaga, Spain, 11–14 May) and published in The Journal of Internal Medicine shows that, in survivors of breast cancer, having an unhealthy metabolic ...
Apr 16, 2025
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Significant variation in kidney transplant decision-making revealed among clinicians and centers
Roughly nine in 10 patients awaiting organ transplants in the United States are waiting for kidneys.
Apr 16, 2025
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Menopause at an early age can exacerbate cognitive decline
A team of researchers from the Tohoku University Graduate School of Medicine and Tokyo Metropolitan Institute of Medical Science found that women who entered menopause before the age of 40 had worse cognitive outcomes than ...
Apr 16, 2025
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Turning off protein may help prevent liver cancer
New research from the Centenary Institute has found that switching off a specific protein in liver cells may help prevent the early development of liver cancer.
Apr 16, 2025
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Researchers uncover molecular connection between body fat and anxiety
Researchers at McMaster University have revealed a novel link between body fat (adipose tissue) and anxiety, shedding light on the intricate relationship between metabolism and mental health.
Apr 15, 2025
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Research reveals snacking may hinder children's growth
Snacking and grazing throughout the day, as opposed to structured mealtimes, could limit children's growth, finds new research by Cardiff University.
Apr 15, 2025
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Uncovering the molecular drivers of liver cancer
Liver cancer can arise spontaneously from healthy liver tissue. Recently, however, researchers have discovered an increasing correlation between some liver cancers and non-viral chronic liver disease (CLD).
Apr 15, 2025
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Q&A: Physicians discuss innovating kidney care in patients with cancer
Raad B. Chowdhury, MD, and Shruti Gupta, MD, MPH, are onconephrologists in the Division of Nephrology at Brigham and Women's Hospital (BWH). They are first and senior authors, respectively, of a paper recently published in ...
Apr 15, 2025
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Mediterranean diet and exercise may slow bone loss in aging women
A three-year lifestyle intervention based on a reduced-calorie Mediterranean diet combined with physical activity helped mitigate age-related bone mineral density loss in older women with metabolic syndrome, according to ...
How mothers adapt to the metabolic demands of nursing
Nursing poses major metabolic demands on mothers, to which they respond by eating more and saving energy to sustain milk production. There are significant hormonal changes during lactation, but how they lead to metabolic ...
Apr 10, 2025
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Premenstrual dysphoric disorder: Social media users claim antihistamines help symptoms—here's what the evidence says
A number of videos have surfaced recently on social media with women claiming that common medications used to treat allergies and heartburn have helped them manage symptoms of premenstrual dysphoric disorder (PMDD). But is ...
Apr 10, 2025
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Scientists propose a targeted lysosomal dysfunction approach for glioblastoma treatment
Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in Nature Communications on how the targeted suppression of lysosome function may lead to brain cancer therapy.
Apr 9, 2025
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Mitochondrial protein synthesis deficiency tied to fetal anemia
A research team from the International Research Center for Medical Sciences (IRCMS) at Kumamoto University has identified a novel mechanism linking fetal anemia to disrupted intracellular iron distribution due to impaired ...
Apr 9, 2025
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Fasting linked to 20% survival boost in colorectal cancer patients
Fasting has shown its potential to reduce colorectal cancer risk by triggering cellular changes that may slow tumor growth, with a study demonstrating a 20% improvement in overall survival. However, since cancer is also influenced ...
Apr 9, 2025
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