Scientists discover kidney cancers rely on mitochondrial metabolism to metastasize
Contrary to how tumors operate while still in the kidney, metastatic kidney cancers rely heavily on mitochondrial metabolism, according to research from Children's Medical Center Research Institute at UT Southwestern (CRI) ...
19 hours ago
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Females' and males' muscles differ in sugar and fatty acid handling, study finds
Females' and males' muscles differ in glucose and fatty acid handling—but regular physical activity quickly triggers similar beneficial metabolic changes in the muscles of both sexes, new research to be presented at the ...
10 hours ago
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Researchers reveal a novel mechanism of mechanical regulation of bone homeostasis
Professor Changjun Li and his colleagues at Xiangya Hospital of Central South University have published a research paper titled "Mechanical protein polycystin-1 directly regulates osteoclastogenesis and bone resorption" in ...
11 hours ago
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Study of fasting and ketogenic diet reveals a new vulnerability of pancreatic tumors
Scientists at UC San Francisco have discovered a way to get rid of pancreatic cancer in mice by putting them on a high fat, or ketogenic, diet and giving them cancer therapy.
Aug 14, 2024
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A new class of beige fat cells that burn energy via 'futile cycles' could lead to better metabolic health
Fat cells come in three colors: white, brown, and beige. White fat cells store fat in our body as an energy reserve. We need these cells, but having too many creates health problems.
Aug 14, 2024
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Chemokine receptor study identifies potential therapies to address sex-related weight gain and disease
A decline in estrogen during menopause causes changes in body fat distribution and associated cardiovascular and metabolic disease, but a new study identifies potential therapies that might one day reverse these unhealthy ...
Aug 14, 2024
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Study highlights potential for using TMAO—a digestive by-product—to predict heart failure risk
New Cleveland Clinic and Tufts University research shows that elevated levels of the gut microbiome trimethylamine N-oxide (TMAO) pathway led to a higher risk of heart failure independent of other risk factors, according ...
Aug 14, 2024
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Changes in the brain detected in severe PMS
It is possible to see changes in both brain function and structure in women with premenstrual dysphoric disorder, which is a severe form of PMS. This is shown in a new doctoral thesis at Umeå University, Sweden. The changes ...
Aug 14, 2024
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Severe menopause symptoms may take toll on brain health
With more than 24 million people globally living with dementia without a cure in sight, there is a lot of focus on ways to prevent and delay cognitive impairment. A new study suggests that severe menopause symptoms such as ...
Aug 14, 2024
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New research explores the urea cycle's strong connection to fatty liver disease
An Indiana University School of Medicine physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States. By identifying the critical ...
Aug 13, 2024
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Significant link found between heme iron, found in red meat and other animal products, and type 2 diabetes risk
Higher intake of heme iron, the type found in red meat and other animal products—as opposed to non-heme iron, found mostly in plant-based foods—was associated with a higher risk of developing type 2 diabetes (T2D) in ...
Aug 13, 2024
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Could targeting metabolism treat blood clots in antiphospholipid syndrome?
Neutrophils are an important type of white blood cell that help your immune system fight infections. One of the many ways neutrophils help is by capturing germs in sticky, spider web-like structures called neutrophil extracellular ...
Aug 13, 2024
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How personalized medicine helps to control the effects of acromegaly earlier
New research has taken a significant step in terms of research and care for acromegaly, a rare disease caused by an excess of growth hormone secretion, which occurs in over 99% of cases due to a generally benign pituitary ...
Aug 13, 2024
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GLP-1 RA use linked to lower rates of hyperkalemia in type 2 diabetes
Treatment with glucagon-like peptide 1 receptor agonists (GLP-1 RAs) is associated with lower rates of hyperkalemia and a lower rate of renin-angiotensin system inhibitor (RASi) discontinuation compared with treatment with ...
Aug 13, 2024
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Scientists elucidate age and gender disparities in cardiometabolic phenotypes and lipidomic signatures
With the aging of the global population, the prevalence of metabolic diseases has significantly increased over the past two decades. Meanwhile, China grapples with the largest population aged 65 years and older and a faster ...
Aug 13, 2024
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Tirzepatide for type 2 diabetes associated with lower risks for mortality, adverse heart, kidney events
For patients with type 2 diabetes, treatment with tirzepatide (a dual glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide receptor agonist) is associated with lower risks for all-cause mortality and adverse ...
Aug 12, 2024
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'Star Wars' star has Graves' disease: What is this disorder?
"Star Wars" actor Daisy Ridley has been diagnosed with an autoimmune disorder that can come with serious consequences: heart failure, stroke and thinning bones, just to name a few. With more than 3.3 million Americans affected ...
Aug 12, 2024
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Remission of type 2 diabetes feasible with soup and shake diet intervention
A behavioral intervention designed to support weight loss can yield remission of type 2 diabetes, according to a study published online Aug 5 in The Lancet Diabetes & Endocrinology.
Aug 9, 2024
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Experts provide further proof of the role testosterone plays in preventing severe COVID-19
A new study has revealed important information about how a patient's testosterone level can help protect them from severe COVID-19. Previous research involving Swansea University investigated how sex hormones are likely to ...
Aug 9, 2024
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Eating for necessity or pleasure? There is a brain circuit for that
People eat either because they are hungry or for pleasure, even in the absence of hunger. While hunger-driven eating is fundamental for survival, pleasure-driven feeding may accelerate the onset of obesity and associated ...
Aug 8, 2024
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HbA1c stability tied to lower risk for Alzheimer's disease and related dementias
Increased glycated hemoglobin (HbA1c) stability within patient-specific target ranges is associated with a lower risk for Alzheimer's disease and related dementias (ADRD), according to a study published online Aug. 2 in JAMA ...
Aug 8, 2024
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Eating disorder risks elevated among women with PCOS, analysis of data suggest
Women with the common reproductive and metabolic condition polycystic ovary syndrome (PCOS) face a greater risk of developing bulimia, binge eating disorder and disordered eating, according to new research published in The ...
Aug 8, 2024
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Optimizing training around your menstrual cycle? New research shows that might not be that simple
Many women experience physical and psychological symptoms that fluctuate during their menstrual cycles. Motivation, how ready you feel to train, and physical well-being may be affected. Therefore, there has been a lot of ...
Aug 7, 2024
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