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Endocrinology & Metabolism news

Cardiology

Study proposes new heart failure treatment targeting abnormal hormone activity

Duke-NUS scientists and their collaborators have discovered a potential new treatment for heart failure with preserved ejection fraction (HFpEF), a type of heart disease that is notoriously difficult to treat. The team discovered ...

Neuroscience

Research suggests myelin fatty acid metabolism could serve as an energy reserve for the central nervous system

The brains of mammals expend a significant amount of energy in the form of adenosine triphosphate (ATP). This is the molecule that cells use to transfer energy, ultimately fueling several biological processes.

Endocrinology & Metabolism

How male hormones regulate skeletal muscle function

Male hormones (androgens), as their name implies, have an important role in promoting the formation of male sexual characteristics (secondary sexual characteristics). In addition, androgens have anabolic effects, as indicated ...

Diabetes

Novel regulator of glucose transport in adipose tissue discovered

The role of the adapter protein PICALM (phosphatidylinositol-binding clathrin assembly protein) in the development of Alzheimer's disease is well documented. Researchers from the German Institute of Human Nutrition Potsdam-Rehbruecke ...

Endocrinology & Metabolism

Study looks at impact of peritoneal dialysis on thyroid function

Patients undergoing peritoneal dialysis (PD) have significantly higher thyroxine (T4) concentrations than hemodialysis (HD) patients and higher free T4 (FT4) concentrations at 12 and 24 months, according to a study published ...

Overweight & Obesity

Guidance provided for management of obesity in kidney disease

In a report issued by the American Society of Nephrology and published online Sept. 18 in the Journal of the American Society of Nephrology, guidance is presented for the management of obesity in persons with kidney disease.

Gerontology & Geriatrics

The pros and cons of hormone therapy for aging transgender women

An estimated 71% of transgender women use or intend to use gender-affirming hormone therapy (GAHT). Although sample sizes are comparatively small, there are studies that demonstrate psychological advantages of GAHT, whereas ...

Obstetrics & gynaecology

What's new and what works in the treatment of hot flashes?

Hot flashes are one of the most commonly reported symptoms of the menopause transition. Over time, a wide array of hormone and nonhormone medications, as well as nonpharmacologic remedies, have been developed to help menopausal ...

Obstetrics & gynaecology

A teen girl's diet could impact her odds for menstrual pain

While working on a senior research project as part of her undergraduate degree from Rutgers University, Serah Sannoh decided to analyze peer-reviewed studies on diet and menstrual period pain, partly because of her own struggles ...

Diseases, Conditions, Syndromes

Hormone protects against development of fatty liver

A group at MedUni Vienna has identified a regulatory loop controlled by leptin, by which this adipocyte-derived hormone regulates hepatic lipid metabolism via the autonomic nervous system. The study, published in Cell Metabolism, ...

Diabetes

Widespread dysregulation of metabolism in type 2 diabetes

Using state of the art techniques, researchers from Uppsala University have shown that the metabolism in patients with type 2 diabetes and prediabetes was much more disturbed than previously known, and that it varied between ...

Alzheimer's disease & dementia

Metabolism linked to brain health

Every three seconds, someone in the world is diagnosed with dementia. And while there is no known cure, changes in the brain can occur years before a dementia diagnosis.

Genetics

Genetics and diet influence bile acid homeostasis

EPFL scientists have used a systems genetics approach to unravel novel genetic and environmental modulators of bile acid homeostasis. Their findings provide new insights into the regulatory mechanisms of bile acid homeostasis ...