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Gerontology & Geriatrics news
Genetics
Q&A: How cryptic mitochondrial DNA mutations reveal a hidden layer of the aging process
New research published in Nature Communications into hidden mutations in mitochondrial DNA has uncovered how high mutational levels coincide with later life and link to aging markers.
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Diseases, Conditions, Syndromes
Known risk factors alone do not explain disease accumulation, finds study
As the population ages, multimorbidity, or when a patient has multiple diseases at once, is becoming increasingly common. The onset of one disease increases the risk of developing other diseases, making it necessary to investigate ...
1 hour ago
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Clinical trial demonstrates the impact of therapeutic plasma exchange on biological age
A first-of-its-kind clinical trial shows that therapeutic plasma exchange (TPE) combined with intravenous immunoglobulin reduced biological age on average by 2.6 years, as measured by multi-omic biomarkers. Results of the ...
1 hour ago
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Combination of rapamycin and trametinib extends mouse lifespan by about 30%, study finds
Researchers at the Max Planck Institute for Biology of Aging have discovered that the combination of the two cancer drugs, rapamycin and trametinib, significantly extends the lifespan of mice. The work has been published ...
4 hours ago
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How intestinal bacteria influence aging of blood vessels
The aging of the innermost cell layer of blood vessels leads to cardiovascular diseases. Researchers at UZH have now shown for the first time that intestinal bacteria and their metabolites contribute directly to vascular ...
5 hours ago
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Silent X chromosome awakens with age: New explanation for sex differences in age-related diseases
Women age differently from men when it comes to health—particularly in conditions like cardiovascular disease and neurodegenerative disorders such as dementia and Parkinson's.
May 27, 2025
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Refined aging measurement method reveals trajectories of healthspan and lifespan in older people
A newly refined method for measuring the Pace of Aging in population-based studies provides a powerful tool for predicting risks associated with aging, including chronic illness, cognitive impairment, disability, and mortality. ...
May 27, 2025
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Napping behaviors predict mortality risk in middle-to-older aged adults
A new study to be presented at the SLEEP 2025 annual meeting found that certain objectively measured daytime napping behaviors are associated with an increased risk of mortality for middle-to-older aged adults.
May 27, 2025
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How older adults adapted to health care challenges during the COVID-19 pandemic
Public health care emergencies, such as the COVID-19 pandemic, can drastically disrupt health care systems with long-term repercussions. The effects of such health care crises are more pronounced in the aging population, ...
May 27, 2025
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Why carrying spuds and playing sudoku could be good measures of your overall health
While aging is inevitable, aging well is something we can influence. It's not just about the number of candles on your birthday cake—it's whether you've got the puff to blow them out, the balance to carry the cake and the ...
May 27, 2025
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Majority of UK hospitals failing to screen older surgical patients for frailty
New research from the Royal College of Anesthetists (RCoA) and the University of Nottingham reveals that nearly three-quarters (71%) of U.K. hospitals are not routinely screening older surgical patients aged 60 and older ...
May 27, 2025
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National audit reveals key strengths and opportunities for medication oversight in Australian aged care
A new national audit led by Monash University has shed light on how medication use is governed in Australian residential aged care, revealing wide variation in the structure and function of Medication Advisory Committees ...
May 26, 2025
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Using testosterone gel to treat women recovering from hip fractures provides no added benefits, clinical trial finds
Hip fractures, often a result of a fall, are the most serious type of osteoporotic fracture because they are accompanied by considerable pain, loss of muscle and bone strength, reduced mobility and independence with daily ...
May 24, 2025
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Skin cancer is a growing threat to older adult men as global population ages
Researchers at the First Affiliated Hospital of Chongqing Medical University in China have uncovered a sharply rising burden of skin cancer in older adults driven largely by population growth and affecting men twice as often.
Timing and consistency of activity linked to better fitness in older adults
Some people spring into action at dawn, while others prefer a slower start to their day. Whether you rise with a grin or a groan, scientists say your internal clock—known as the circadian rhythm—might influence that behavior ...
May 23, 2025
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Mitochondrial DNA mutation accumulation may not be a determining factor in aging
The human genome is broadly classified into the genome residing in the cell nucleus (nuclear DNA) and the genome residing in the mitochondria (mitochondrial DNA: mtDNA). Mitochondria are cell organelles that produce energy ...
May 23, 2025
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Early testing could make risky falls a thing of the past for elderly people
As we get older, our bodies stop performing as they once did. We aren't as strong as we once were, we don't see as well as we used to and we start becoming less mobile. These changes inevitably lead to almost one‑third ...
May 22, 2025
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Positive mindset about aging in over-60s linked to better recovery after a fall
There is a strong association between an older person's view of how they are aging and how well they will physically recover after a fall.
May 22, 2025
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Why gait quality matters as you age
Walking is one of the most important things we do for our quality of life. In fact, research shows it contributes more than any other physical activity to how well we live day to day. Yet one in three people over the age ...
May 22, 2025
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Never too old: Medication improves survival rates after a first heart attack even in patients over age 90
Researchers have found that prescribing guideline-directed medical treatment (GDMT), regardless of the number of medications, can improve survival rates in patients 90 years of age and older following their first heart attack, ...
May 22, 2025
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Aged care staffing levels are on the rise—but is it helping to improve quality of care?
Efforts to increase direct care staffing levels in aged care homes are working but a new study raises a critical question: Is this enough to improve quality of care for older people?
May 22, 2025
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'Barcodes' written into DNA reveal how blood ages
A study in the journal Nature explains how age reshapes the blood system. In both humans and mice, a few stem cells, or "clones," outcompete their neighbors and gradually take over blood production. The blood stem cell reservoir ...
May 21, 2025
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Vitamin D supplements help slow telomere shortening linked to biological aging
Results from the VITAL randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, protective caps at the ends of chromosomes that shorten during aging and are linked to the development of ...
May 21, 2025
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Classifying older adults requiring long-term care into five groups and clarifying their prognosis
Older adults requiring long-term care frequently experience multiple disabilities, with considerable variation in the combinations of these impairments. Because of this diversity, interventions that focus on a single impairment ...
May 21, 2025
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Study suggests engaging in social activities may prolong life
A study in the Journal of the American Geriatrics Society indicates that social engagement may help older individuals live longer.
May 21, 2025
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