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Gerontology & Geriatrics news

Gerontology & Geriatrics

New organ-on-a-chip platform allows the testing of cancer vaccine efficacy in aging populations

Dr. Vadim Jucaud's lab at the Terasaki Institute has introduced a new organ-on-a-chip platform that recapitulates age-dependent immune responses, offering a more accurate testing bed for evaluating cancer vaccine performance ...

Psychology & Psychiatry

Friendship can be an important lifeline for older adults without children

Friendship can be one of the keys to staying healthier later in life—that was one of the key findings from new research at the University of New Hampshire that took a closer look into the growing public health concern of ...

Psychology & Psychiatry

Who are the loneliest Americans?

Middle-aged Americans are most likely to feel the pinch of loneliness in their lives these days, a new AARP survey has found.

Gerontology & Geriatrics

Age-related muscle wasting tied to cell recycling defect

Two related studies published today in Nature Metabolism show that a specialized intracellular recycling mechanism—chaperone-mediated autophagy (CMA)—is essential for muscle health.

Diabetes

Diabetes drugs may help older adults slow frailty

A new study shows that older adults with type 2 diabetes who start treatment with sodium–glucose cotransporter-2 (SGLT-2) inhibitors—such as empagliflozin (Jardiance) and dapagliflozin (Farxiga)—or glucagon-like peptide-1 ...

Psychology & Psychiatry

Navigating grief in the aged care system

Grief for families in the aged care system begins long before the death of their loved ones, new research has found, highlighting the need for a systemic rethink of how grief is understood and supported.

Genetics

Why important genes 'go quiet' as we get older

The human gut renews itself faster than any other tissue: every few days, new cells are created from specialized stem cells. However, as we get older, epigenetic changes build up in these stem cells. These are chemical markers ...

Inflammatory disorders

Chronic pruritus prevalent among older adults

Chronic pruritus is prevalent among older adults and is associated with moderately impaired pruritus-specific quality of life, according to a study published online Nov. 10 in Acta Dermato Venereologica.

Overweight & Obesity

Weight change may contribute to cognitive decline in older adults

Adults over 65 whose weight decreases or fluctuates by more than 5% may experience faster cognitive decline, according to researchers in the Department of Nutritional Sciences at Penn State. The team has published its findings ...

Health

Meal timing in later life may matter for health and longevity

As we age, what and how much we eat tends to change. However, how meal timing relates to health remains less understood. Researchers at Mass General Brigham and their collaborators studied changes to meal timing in older ...

Cardiology

Hurricane Sandy linked to lasting heart disease risk in elderly

Although the material damage from 2012's Hurricane Sandy may have been repaired, the storm left a lasting impact on cardiovascular health, according to new findings from Weill Cornell Medicine and New York University researchers.

Neuroscience

How aging drives neurodegenerative diseases

A University of Cologne research team has identified a direct molecular link between aging and neurodegeneration by investigating how age-related changes in cell signaling contribute to toxic protein aggregation.

Gerontology & Geriatrics

Scanner detects bedsores earlier, saving lives and costs

In 2010, UCLA nursing professor Barbara Bates-Jensen traveled to Haiti to direct and provide wound care for victims of a 7.0-magnitude earthquake that had killed or injured more than half a million people and left 5 million ...

Surgery

Too old for a new heart?

Across a spectrum of diseases from cancer to heart failure, older patients face systemic bias in their treatment. Individuals in the 70s, 80s, and 90s are less likely to be offered the same options for care as younger patients. ...