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Inflammatory disorders news

Diseases, Conditions, Syndromes

Treatment for chronic rhinitis yields significant clinical improvements

Neurent Medical, a company developing non-surgical interventions to treat chronic inflammatory sinonasal diseases, has released positive six-month results from the PARAGON clinical study in Ear, Nose & Throat Journal.

Inflammatory disorders

A faulty iron hormone in the skin may be the root cause of psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2–3% of the global population. The condition is characterized by red, scaly patches that impact the ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Medications

FDA approves Bimzelx for three new indications

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...

Diseases, Conditions, Syndromes

Houston pollen count has spiked dramatically over the last decade

New data from the Houston area reveals spiking levels of ragweed, elm and cedar elm pollen as well as mold spore counts as we enter the fall season. An allergy expert at Baylor College of Medicine breaks down this information ...

Inflammatory disorders

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.

Inflammatory disorders

Diagnostic tool identifies puzzling inflammatory diseases in kids

RNA performs a number of biological duties, from delivering genetic information to manufacturing proteins. But RNA is also expelled from cells via cell death or active release, and can then find its way into blood plasma.

Dentistry

Altered blood markers detected in individuals with periodontitis

Individuals with periodontitis have altered concentrations of various proteins in their blood, according to a new study from Umeå University, Sweden. These findings pave the way for research into biomarkers for periodontitis ...

Inflammatory disorders

How the health of your gut microbiome can affect your skin

The skin is the largest organ of the human body. Not only does it act as the first line of defense against external stressors such as environmental toxins, pathogens and pollutants, our skin can also reveal much about our ...

Diseases, Conditions, Syndromes

Blocking immune system 'messenger' may treat severe asthma

Asthma is more dangerous than many people realize. An estimated 10 Americans die everyday from asthma, and the disease leads to around 439,000 hospitalizations and 1.3 million emergency room trips each year.

Immunology

Immune cell movement worse in older females, mice study finds

According to a new study, older female mice had more immune cells entering areas of the body where they should not have, demonstrating that sex differences contribute to age-related inflammation, which should be considered ...

Inflammatory disorders

A novel way to diagnose early-onset atopic dermatitis using sebum

Eczema is an inflammatory skin condition that often affects infants as young as one to two months. Among the various types of eczema seen in infants, early-onset atopic dermatitis (AD), characterized by psychological stress ...

Genetics

Scientists find treatment for rare genetic skin disorder

Researchers at the National Institutes of Health and their colleagues have identified genomic variants that cause a rare and severe inflammatory skin disorder, known as disabling pansclerotic morphea, and have found a potential ...

Immunology

Summer thunderstorms can leave asthma-sufferers breathless

As the weather heats up, many are looking forward to getting outside for some fun in the sun. But for asthma-sufferers, the summer season can present dangerous conditions through asthma triggers that many are unaware of, ...

Inflammatory disorders

Microscopic colitis and the risk of acute pancreatitis

In a nationwide Swedish study of more than 12,000 patients with microscopic colitis (MC), researchers from Sahlgrenska University Hospital and Karolinska Institutet found an increased risk of acute pancreatitis compared to ...

Inflammatory disorders

Study may explain why high-sugar diets can worsen IBD

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

Medical research

Learning from bats to fight inflammation in humans

By studying the unusual ability of bats to host viruses without significant illness, scientists at Duke-NUS Medical School have discovered a protein that could unlock new strategies for fighting inflammatory diseases in humans.