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Inflammatory disorders news

Diseases, Conditions, Syndromes

Treatment for chronic rhinitis yields significant clinical improvements

Neurent Medical, a company developing non-surgical interventions to treat chronic inflammatory sinonasal diseases, has released positive six-month results from the PARAGON clinical study in Ear, Nose & Throat Journal.

Inflammatory disorders

A faulty iron hormone in the skin may be the root cause of psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2–3% of the global population. The condition is characterized by red, scaly patches that impact the ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Medications

FDA approves Bimzelx for three new indications

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...

Diseases, Conditions, Syndromes

Houston pollen count has spiked dramatically over the last decade

New data from the Houston area reveals spiking levels of ragweed, elm and cedar elm pollen as well as mold spore counts as we enter the fall season. An allergy expert at Baylor College of Medicine breaks down this information ...

Inflammatory disorders

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.

Inflammatory disorders

Diagnostic tool identifies puzzling inflammatory diseases in kids

RNA performs a number of biological duties, from delivering genetic information to manufacturing proteins. But RNA is also expelled from cells via cell death or active release, and can then find its way into blood plasma.

Dentistry

Altered blood markers detected in individuals with periodontitis

Individuals with periodontitis have altered concentrations of various proteins in their blood, according to a new study from Umeå University, Sweden. These findings pave the way for research into biomarkers for periodontitis ...

Inflammatory disorders

How the health of your gut microbiome can affect your skin

The skin is the largest organ of the human body. Not only does it act as the first line of defense against external stressors such as environmental toxins, pathogens and pollutants, our skin can also reveal much about our ...

Immunology

Potential long-term treatment for asthma found

A possible way to tackle one of the underlying causes of asthma has been developed by researchers from Aston University and Imperial College London. In tests in mice, the researchers were able to virtually eliminate asthmatic ...

Oncology & Cancer

'Inside out' signaling promotes tumor growth

A specific immune system kinase has been found to promote tumor inflammation and progression, according to a study published in Nature Communications.

Inflammatory disorders

Update on acute liver inflammation of unknown origin in children

Unexplained cases of acute liver inflammation in children, especially in the United Kingdom (U.K.), were reported earlier this year. In response, the European Reference Network on Hepatological Diseases (ERN RARE-LIVER) conducted ...

Medical research

Dermatologist visits shorter for Asian psoriasis patients

Asian patients with psoriasis receive significantly less face-to-face time with a dermatologist than patients of other races and ethnicities, according to a research letter published online Aug. 3 in JAMA Dermatology.

Medical research

Inflammation accelerates aging of the hematopoietic system

In mice, inflammation in early to mid-life leads to a permanent decline in functional blood stem cells, according to a recent publication by scientists from the German Cancer Research Center (DKFZ) and the Stem Cell Institute ...

Medications

Seven in ten people with asthma could be using less medication

Seven out of ten Australians with asthma aged over 12 years may be prescribed too much preventer medicine. In Australian Prescriber Prof. Helen Reddel and coauthors from the Woolcock Institute of Medical Research write about ...

Inflammatory disorders

Teleconsultation to prevent skin conditions in infants

A recent publication in JMIR Pediatrics and Parenting reported that mothers of infants are prone to experiencing parenting stress, which adversely affects mothers' and children's well-being. Additionally, studies have reported ...

Diseases, Conditions, Syndromes

New acne treatment 'exciting', but Europe will have to wait

A new drug touted as the first real breakthrough in acne treatment in decades has been available for months in the United States, but when it will hit the shelves in Europe and elsewhere remains unclear.

Inflammatory disorders

Familial risk estimated for inflammatory bowel disease

The risk for a patient with inflammatory bowel disease (IBD) having a first-degree relative (FDR) with IBD is increased, according to a study published in the August issue of Alimentary Pharmacology & Therapeutics.

Psychology & Psychiatry

Feeling stressed? It can show in your skin, hair and nails

Stress is a part of life. Whether your stressors are small or large, they can impact both your mental and physical well-being. While we can't completely remove stress from our lives, board-certified dermatologists can recommend ...

Medications

Asthma medication not working? Try another

People who supplement rescue inhalers with a second asthma medication sometimes get little relief at first, but there's good news: Those who keep trying different options often find a medication that works, according to Rutgers ...

Medications

OCS-sparing effect of dupilumab for severe asthma maintained

Long-term treatment of severe asthma with dupilumab supports sustained reduction in oral corticosteroid (OCS) dosage and improvement in clinical end points for up to 96 weeks, according to a study published in the July issue ...

Inflammatory disorders

Smoking is causally associated with psoriasis risk

Smoking, but not alcohol consumption, is causally associated with psoriasis, according to a study published online June 28 in the British Journal of Dermatology.

Inflammatory disorders

AI system could help clinicians assess psoriasis severity

An artificial intelligence (AI) system could aid clinicians in assessing psoriasis severity, according to a short report published online June 28 in the Journal of the European Academy of Dermatology and Venereology.

Immunology

Adjusting diet has pros and cons for treating eczema, study says

People with mild or moderate eczema may gain some relief from their condition by adjusting their diets, but there are important downsides that make diets for eczema not a choice to take lightly, says McMaster University researcher ...

Diseases, Conditions, Syndromes

Urgent health care use up for adults with concomitant eczema, asthma

Adults with concomitant atopic dermatitis (AD) and asthma have an increased risk for urgent health care use, according to a study published online July 7 in the Journal of the European Academy of Dermatology & Venereology.

Medications

Marijuana plant might hold key to treating chronic inflammation

Several minor cannabinoids contained in the cannabis plant "strongly inhibit" the activation of human immune cells that lead to chronic inflammation, according to physiologists at The Queen's Medical Center and University ...